Yongli Shan, John H. Abel, Yan Li, Mariko Izumo, Kimberly H. Cox, Byeongha Jeong, Seung-Hee Yoo, David P. Olson, Francis J. Doyle III, & Joseph S. Takahashi. Neuron, 2020.
Mazuski C, Abel JH, Chen SP, Hermanstyne TO, Jones JR, Simon T, Doyle FJ, Herzog ED. Entrainment of circadian rhythms depends on firing rates and neuropeptide release of VIP SCN neurons. Neuron, 2018. doi:10.1016/j.neuron.2018.06.029
V Carmona-Alcocer, JH Abel, TC Sun, LR Petzold, FJ Doyle III, CL Simms, ED Herzog. “Ontogeny of circadian rhythms and synchrony in the suprachiasmatic nucleus,” Journal of Neuroscience, 2017. doi:10.1523/JNEUROSCI.2006-17.2017
J.H. Abel, B. Drawert, A. Hellander, and L.R. Petzold, “GillesPy: a Python package for stochastic model building and simulation,” IEEE Life Sciences Letters, 2017. doi: 10.1109/LLS.2017.2652448
J.H. Abel and F.J. Doyle III. “A systems theoretic approach to analysis and control of mammalian circadian dynamics.” Chemical Engineering Research and Design, 2016. doi:10.1016/j.cherd.2016.09.033
Harvard SEAS: “Research sheds light the neural structure that controls our sleep, eating habits, hormones and more.” See within for press from our most recent study of the circadian clock. Harvard SEAS: here UCSB Current: here This has been featured elsewhere, including: ExtremeTech The Daily Mail
While the overall effects of circadian activities have been studied, relatively little is understood about the structure of the network of brain cells as they communicate to control the synchronization process. In a paper that appears in the Proceedings of the National Academy of Sciences, UC Santa Barbara [and Harvard!] researchers and collaborators infer the […]
Developing control systems for medical applications poses significant challenges, some of which are unique to this field. Physiological systems involve a multitude of interacting subsystems and networks, with multiple feedforward and feedback loops. The dynamics vary both between different individuals, and within the same individual over time. Measurement and estimation of both inter- and intra-patient […]
The success of the human genome project has ushered in a new era that emphasizes a systemic or integrated approach to ascertain the cellular behavior arising from complex cellular networks. Scientists are now embarking on a quest to elucidate the organization and control of cellular networks that underlie the phenotypic behavior of a cell; these […]
Sansum Diabetes Research Institute
Our experimental collaborators, a research center devoted to the prevention, treatment and cure of diabetes http://www.sansum.org/
Developing control systems for medical applications poses significant challenges, some of which are unique to this field. Physiological systems involve a multitude of interacting subsystems and networks, with multiple feedforward and feedback loops. The dynamics vary both between different individuals, and within the same individual over time. Measurement and estimation of both inter- and intra-patient […]
The success of the human genome project has ushered in a new era that emphasizes a systemic or integrated approach to ascertain the cellular behavior arising from complex cellular networks. Scientists are now embarking on a quest to elucidate the organization and control of cellular networks that underlie the phenotypic behavior of a cell; these […]
