Drawing from a systems science background, my research in systems biology starts with developing statistical inference and visualization tools to identify gene/pathway/functional biomarkers, and then utilizes them to construct mathematical models that predict disease progression. Finally, I apply systems and control theory to analyze their dynamic characterics and suggest potential therapeutic targets. I am currently working towards biomarker identification and fear conditioning neurocircuits for Post-Traumatic Stress Disorder, which is a severe anxiety disorder triggered from traumatic events.
Area of interest
Systems Biology, Mathematical Modeling, Bio-inspired Control, Nanobiosystems, Robotics, Nonlinear Dynamics and Control, Game Theory, Controlled drug delivery, Complex System.
B.S., Automatic Control, Xiamen University, China, 2000
M.S., Institute of Systems Science, Chinese Academy of Sciences, 2003
M.S. & Ph.D., Washington University, St. Louis, 2008
G.S. Thakur, B.J. Daigle Jr, K.R. Dean, Y. Zhang, M. Rodriguez-Fernandez, R. Hammamieh, R. Yang, M. Jett, J. Palma, L.R. Petzold, F.J. Doyle III, “Systems biology approach to understanding post-traumatic stress disorder,” Molecular bioSystems, Jan 2015. [DOI]