Publications
Utilization of machine learning for identifying symptom severity military-related PTSD subtypes and their biological correlates
Carole E. Siegel, Eugene M. Laska, Ziqiang Lin, Mu Xu, Duna Abu-Amara, Michelle K. Jeffers, Meng Qian, Nicholas Milton, Janine D. Flory, Rasha Hammamieh, Bernie J. Daigle Jr., Aarti Gautam, Kelsey R. Dean, Victor I. Reus, Owen M. Wolkowitz, Synthia H. Mellon, Kerry J. Ressler, Rachel Yehuda, Kai Wang, Leroy Hood, Francis J. Doyle III, Marti Jett & Charles R. Marmar (2021) Translational Psychiatry 11(227).
Carole E. Siegel, Eugene M. Laska, Ziqiang Lin, Mu Xu, Duna Abu-Amara, Michelle K. Jeffers, Meng Qian, Nicholas Milton, Janine D. Flory, Rasha Hammamieh, Bernie J. Daigle Jr., Aarti Gautam, Kelsey R. Dean, Victor I. Reus, Owen M. Wolkowitz, Synthia H. Mellon, Kerry J. Ressler, Rachel Yehuda, Kai Wang, Leroy Hood, Francis J. Doyle III, Marti Jett & Charles R. Marmar (2021) Translational Psychiatry 11(227).
Machine Learning-Based Anomaly Detection Algorithms to Alert Patients Using Sensor Augmented Pump of Infusion Site Failures
Meneghetti, L., Dassau, E., Doyle III, F. J., & Del Favero, S. (2021). Journal of Diabetes Science and Technology.
Meneghetti, L., Dassau, E., Doyle III, F. J., & Del Favero, S. (2021). Journal of Diabetes Science and Technology.
Epigenetic biotypes of post-traumatic stress disorder in war-zone exposed veteran and active duty males
Ruoting Yang, Aarti Gautam, Derese Getnet, Bernie J. Daigle, Stacy Miller, Burook Misganaw, Kelsey R. Dean, Raina Kumar, Seid Muhie, Kai Wang, Inyoul Lee, Duna Abu-Amara, Janine D. Flory, The PTSD Systems Biology Consortium, Leroy Hood, Owen M. Wolkowitz, Synthia H. Mellon, Francis J. Doyle III, Rachel Yehuda, Charles R. Marmar, Kerry J. Ressler, Rasha Hammamieh & Marti Jett (2020) Molecular Psychiatry.
Ruoting Yang, Aarti Gautam, Derese Getnet, Bernie J. Daigle, Stacy Miller, Burook Misganaw, Kelsey R. Dean, Raina Kumar, Seid Muhie, Kai Wang, Inyoul Lee, Duna Abu-Amara, Janine D. Flory, The PTSD Systems Biology Consortium, Leroy Hood, Owen M. Wolkowitz, Synthia H. Mellon, Francis J. Doyle III, Rachel Yehuda, Charles R. Marmar, Kerry J. Ressler, Rasha Hammamieh & Marti Jett (2020) Molecular Psychiatry.
More time in glucose range during exercise days than sedentary days in adults living with type 1 diabetes
Michael Riddell, Zoey Li, Roy W. Beck, Robin Gal, Peter G. Jacobs, Jessica R. Castle, Melanie Gillingham, Mark A. Clements, Susana R. Patton, Eyal Dassau, Francis J. Doyle III, Corby Martin, Peter Calhoun, and Michel Rickels, (2020). Diabetes Technology & Therapuetics.
Michael Riddell, Zoey Li, Roy W. Beck, Robin Gal, Peter G. Jacobs, Jessica R. Castle, Melanie Gillingham, Mark A. Clements, Susana R. Patton, Eyal Dassau, Francis J. Doyle III, Corby Martin, Peter Calhoun, and Michel Rickels, (2020). Diabetes Technology & Therapuetics.
A dual-feedback loop model of the mammalian circadian clock for multi-input control of circadian phase
L. S. Brown & F. J. Doyle III, PLoS Compuational Biology, 2020.
L. S. Brown & F. J. Doyle III, PLoS Compuational Biology, 2020.
A Review of Biomarkers in the Context of Type 1 Diabetes: Biological Sensing for Enhanced Glucose Control
Kelilah L. Wolkowicz , Eleonora M. Aiello, Eva Vargas, Hazhir Teymourian, Farshad Tehrani, Joseph Wang, Jordan E. Pinsker, Francis J. Doyle III, Mary‐Elizabeth Patti, Lori M. Laffel, & Eyal Dassau (2020). Bioengineering and Translational Medicine.
Kelilah L. Wolkowicz , Eleonora M. Aiello, Eva Vargas, Hazhir Teymourian, Farshad Tehrani, Joseph Wang, Jordan E. Pinsker, Francis J. Doyle III, Mary‐Elizabeth Patti, Lori M. Laffel, & Eyal Dassau (2020). Bioengineering and Translational Medicine.
Assessing Mealtime Macronutrient Content: Patient Perceptions versus Expert Analyses via a Novel Phone App
Melanie Gillingham, Zoey Li, Roy W. Beck, Peter Calhoun, Jessica R Castle, Mark A Clements, Eyal Dassau, Francis J. Doyle III, Robin Gal, Peter G. Jacobs, Susana R Patton, Michael Rickels, Michael Riddell, Corby Martin. Diabetes Technology & Therapeutics, 2020.
Melanie Gillingham, Zoey Li, Roy W. Beck, Peter Calhoun, Jessica R Castle, Mark A Clements, Eyal Dassau, Francis J. Doyle III, Robin Gal, Peter G. Jacobs, Susana R Patton, Michael Rickels, Michael Riddell, Corby Martin. Diabetes Technology & Therapeutics, 2020.
Use of the Interoperable Artificial Pancreas System for Type 1 Diabetes Management During Psychological Stress
Jordan E. Pinsker, Sunil Deshpande, Shelly McCrady-Spitzer, Mei Mei Church, Ravinder Jeet Kaur, Jimena Perez, Donna Desjardins, Molly Piper, Corey Reid, Francis J. Doyle, III, Yogish C. Kudva, & Eyal Dassau. Journal of Diabetes Science and Technology, 2020.
Jordan E. Pinsker, Sunil Deshpande, Shelly McCrady-Spitzer, Mei Mei Church, Ravinder Jeet Kaur, Jimena Perez, Donna Desjardins, Molly Piper, Corey Reid, Francis J. Doyle, III, Yogish C. Kudva, & Eyal Dassau. Journal of Diabetes Science and Technology, 2020.
Dual-Color Single-Cell Imaging of the Suprachiasmatic Nucleus Reveals a Circadian Role in Network Synchrony
Yongli Shan, John H. Abel, Yan Li, Mariko Izumo, Kimberly H. Cox, Byeongha Jeong, Seung-Hee Yoo, David P. Olson, Francis J. Doyle III, & Joseph S. Takahashi. Neuron, 2020.
Yongli Shan, John H. Abel, Yan Li, Mariko Izumo, Kimberly H. Cox, Byeongha Jeong, Seung-Hee Yoo, David P. Olson, Francis J. Doyle III, & Joseph S. Takahashi. Neuron, 2020.
Using Iterative Learning for Insulin Dosage Optimization in Multiple-Daily-Injections Therapy for People with Type 1 Diabetes
M. Cescon, S. Deshpande, R. Nimri, F. J. Doyle III, & E. Dassau. IEEE Transactions on Biomedical Engineering, 2020.
M. Cescon, S. Deshpande, R. Nimri, F. J. Doyle III, & E. Dassau. IEEE Transactions on Biomedical Engineering, 2020.
Pre-deployment risk factors for PTSD in active-duty personnel deployed to Afghanistan: a machine-learning approach for analyzing multivariate predictors
Katharina Schultebraucks, Meng Qian, Duna Abu-Amara, Kelsey Dean, Eugene Laska, Carole Siegel, Aarti Gautam, Guia Guffanti, Rasha Hammamieh, Burook Misganaw, Synthia H. Mellon, Owen M. Wolkowitz, Esther M. Blessing, Amit Etkin, Kerry J. Ressler, Francis J. Doyle III, Marti Jett, & Charles R. Marmar, Molecular Psychiatry, 2020.
Katharina Schultebraucks, Meng Qian, Duna Abu-Amara, Kelsey Dean, Eugene Laska, Carole Siegel, Aarti Gautam, Guia Guffanti, Rasha Hammamieh, Burook Misganaw, Synthia H. Mellon, Owen M. Wolkowitz, Esther M. Blessing, Amit Etkin, Kerry J. Ressler, Francis J. Doyle III, Marti Jett, & Charles R. Marmar, Molecular Psychiatry, 2020.
Glycemic Outcomes of Use of CLC Versus PLGS in Type 1 Diabetes: A Randomized Controlled Trial
Sue A. Brown, Roy W. Beck, Dan Raghinaru, Bruce A. Buckingham, Lori M. Laffel, R. Paul Wadwa, Yogish C. Kudva, Carol J. Levy, Jordan E. Pinsker, Eyal Dassau, Francis J. Doyle, Louise Ambler-Osborn, Stacey M. Anderson, Mei Mei Church, Laya Ekhlaspour, Gregory P. Forlenza, Camilla Levister, Vinaya Simha, Marc D. Breton, Craig Kollman, John W. Lum, Boris P. Kovatchev, for the iDCL Trial Research Group. Diabetes Care, 2020.
Sue A. Brown, Roy W. Beck, Dan Raghinaru, Bruce A. Buckingham, Lori M. Laffel, R. Paul Wadwa, Yogish C. Kudva, Carol J. Levy, Jordan E. Pinsker, Eyal Dassau, Francis J. Doyle, Louise Ambler-Osborn, Stacey M. Anderson, Mei Mei Church, Laya Ekhlaspour, Gregory P. Forlenza, Camilla Levister, Vinaya Simha, Marc D. Breton, Craig Kollman, John W. Lum, Boris P. Kovatchev, for the iDCL Trial Research Group. Diabetes Care, 2020.
A DNA methylation clock associated with age-related illnesses and mortality is accelerated in men with combat PTSD
Ruoting Yang, Gwyneth W. Y. Wu, Josine E. Verhoeven, Aarti Gautam, Victor I. Reus, Jee In Kang, Janine D. Flory, Duna Abu-Amara, PTSD Systems Biology Consortium, Leroy Hood, Francis J. Doyle III, Rachel Yehuda, Charles R. Marmar, Marti Jett, Rasha Hammamieh, Synthia H. Mellon, & Own M. Wolkowitz. Molecular Pyschiatry, 2020.
Ruoting Yang, Gwyneth W. Y. Wu, Josine E. Verhoeven, Aarti Gautam, Victor I. Reus, Jee In Kang, Janine D. Flory, Duna Abu-Amara, PTSD Systems Biology Consortium, Leroy Hood, Francis J. Doyle III, Rachel Yehuda, Charles R. Marmar, Marti Jett, Rasha Hammamieh, Synthia H. Mellon, & Own M. Wolkowitz. Molecular Pyschiatry, 2020.
Randomized Crossover Comparison of Automated Insulin Delivery vs. Conventional Therapy using an Unlocked Smartphone with Scheduled Pasta and Rice Meal Challenges in the Outpatient Setting
Sunil Deshpande, Jordan E. Pinsker, Mei Mei Church, Molly Piper, Camille Andre, Jennifer Massa, Francis J. Doyle, Dacid M. Eisenberg, and Eyal Dassau. 2020. Diabetes, Technology, and Therapuetics.
Sunil Deshpande, Jordan E. Pinsker, Mei Mei Church, Molly Piper, Camille Andre, Jennifer Massa, Francis J. Doyle, Dacid M. Eisenberg, and Eyal Dassau. 2020. Diabetes, Technology, and Therapuetics.
Novel Pharmacological Targets for Combat PTSD—Metabolism, Inflammation, The Gut Microbiome, and Mitochondrial Dysfunction
F Saverio Bersani, Synthia H Mellon, Daniel Lindqvist, Jee In Kang, Ryan Rampersaud, Pramod Rajaram Somvanshi, Francis J Doyle, III, Rasha Hammamieh, Marti Jett, Rachel Yehuda, Charles R Marmar, Owen M Wolkowitz, Military Medicine 185, 2020.
F Saverio Bersani, Synthia H Mellon, Daniel Lindqvist, Jee In Kang, Ryan Rampersaud, Pramod Rajaram Somvanshi, Francis J Doyle, III, Rasha Hammamieh, Marti Jett, Rachel Yehuda, Charles R Marmar, Owen M Wolkowitz, Military Medicine 185, 2020.
Randomized Controlled Trial of Mobile Closed-Loop Control
Boris Kovatchev, Stacey M. Anderson, Dan Raghinaru, Yogish C. Kudva, Lori M. Laffel, Carol Levy, Jordan E. Pinsker, R. Paul Wadwa, Bruce Buckingham, Francis J. Doyle, Sue A. Brown, Mei Mei Church, Vikash Dadlani, Eyal Dassau, Laya Ekhlaspour, Gregory P. Forlenza, Elvira Isganaitis, David W. Lam, John Lum, Roy W. Beck, for the iDCL Study Group. Diabetes Care. 2020.
Boris Kovatchev, Stacey M. Anderson, Dan Raghinaru, Yogish C. Kudva, Lori M. Laffel, Carol Levy, Jordan E. Pinsker, R. Paul Wadwa, Bruce Buckingham, Francis J. Doyle, Sue A. Brown, Mei Mei Church, Vikash Dadlani, Eyal Dassau, Laya Ekhlaspour, Gregory P. Forlenza, Elvira Isganaitis, David W. Lam, John Lum, Roy W. Beck, for the iDCL Study Group. Diabetes Care. 2020.
A Randomized, Placebo-Controlled Double-Blind Trial of a Closed-Loop Glucagon System for Post-Bariatric Hypoglycemia
C. M. Mulla, S. Zavitsanou, A. J. Laguna Sanz, D. Pober, L. Richardson, P. Walcott, I. Arora, B. Newswanger, M. J. Cummins, S. J. Prestrelski, F. J. Doyle III, E. Dassau, M. E. Patti. The Journal of Clinical Endocrinology & Metabolism, 2019.
C. M. Mulla, S. Zavitsanou, A. J. Laguna Sanz, D. Pober, L. Richardson, P. Walcott, I. Arora, B. Newswanger, M. J. Cummins, S. J. Prestrelski, F. J. Doyle III, E. Dassau, M. E. Patti. The Journal of Clinical Endocrinology & Metabolism, 2019.
Six-Month Randomized, Multicenter Trial of Closed-Loop Control in Type 1 Diabetes
Sue A. Brown, Boris P. Kovatchev, Dan Raghinaru, John W. Lum, Bruce A. Buckingham, Yogish C. Kudva, Lori M. Laffel, Carol J. Levy, Jordan E. Pinsker, R. Paul Wadwa, Eyal Dassau, Francis J. Doyle, III, Stacey M. Anderson, Mei Mei Church, Vikash Dadlani, Laya Ekhlaspour, Gregory P. Forlenza, Elvira Isganaitis, David W. Lam, Craig Kollman, and Roy W. Beck for the iDCL Trial Research Group. New England Journal of Medicine, 2019.
Sue A. Brown, Boris P. Kovatchev, Dan Raghinaru, John W. Lum, Bruce A. Buckingham, Yogish C. Kudva, Lori M. Laffel, Carol J. Levy, Jordan E. Pinsker, R. Paul Wadwa, Eyal Dassau, Francis J. Doyle, III, Stacey M. Anderson, Mei Mei Church, Vikash Dadlani, Laya Ekhlaspour, Gregory P. Forlenza, Elvira Isganaitis, David W. Lam, Craig Kollman, and Roy W. Beck for the iDCL Trial Research Group. New England Journal of Medicine, 2019.
Multi-omic biomarker identification and validation for diagnosing warzone-related post-traumatic stress disorder
Kelsey R. Dean, Rasha Hammamieh, Synthia H. Mellon, Duna Abu-Amara, Janine D. Flory, Guia Guffanti, Kai Wang, Bernie J. Daigle Jr., Aarti Gaurtam, Inyoul Lee, Ruoting Yang, Lynn M. Almli, F. Saverio Bersani, Nabarun Chakraborty, Duncan Donohue, Kimberly Kerly, Taek-Kyun Kim, Eugene Laska, Min Young Lee, Daniel Lindqvist, Adriana Lori, Liangqun Lu, Burook Misganaw, Seif […]
Kelsey R. Dean, Rasha Hammamieh, Synthia H. Mellon, Duna Abu-Amara, Janine D. Flory, Guia Guffanti, Kai Wang, Bernie J. Daigle Jr., Aarti Gaurtam, Inyoul Lee, Ruoting Yang, Lynn M. Almli, F. Saverio Bersani, Nabarun Chakraborty, Duncan Donohue, Kimberly Kerly, Taek-Kyun Kim, Eugene Laska, Min Young Lee, Daniel Lindqvist, Adriana Lori, Liangqun Lu, Burook Misganaw, Seif […]
Automated Insulin Delivery for Type 1 Diabetes Mellitus Patients using Gaussian Process-based Model Predictive Control
Lukas Ortman, Dawei Shi, Eyal Dassau, Francis J. Doyle III, Berno J. E. Misgeld, and Steffen Leonhardt (2019). American Control Conference (ACC).
Lukas Ortman, Dawei Shi, Eyal Dassau, Francis J. Doyle III, Berno J. E. Misgeld, and Steffen Leonhardt (2019). American Control Conference (ACC).
Iterative Learning Control with Sparse Measurements for Long-Acting Insulin Injections in People with Type 1 Diabetes
Marzia Cescon, Sunil Deshpande, Francis J. Doyle III, and Eyal Dassau (2019). American Control Conference (ACC).
Marzia Cescon, Sunil Deshpande, Francis J. Doyle III, and Eyal Dassau (2019). American Control Conference (ACC).
Mechanistic inferences on metabolic dysfunction in PTSD from an integrated model and multi-omic analysis: Role of glucocorticoid receptor sensitivity
Pramod R. Somvanshi, Synthia H. Mellon, Janine D. Flory, Duna Abu-amara, PTSD Systems Biology Consortium, Owen M. Wolkowitz, Rachel Yehuda, Marti Jett, Leroy Hood, Charles Marmar, and Francis J. Doyle. 2019. American Journal of Physiology: Endocrinology and Metabolism.
Pramod R. Somvanshi, Synthia H. Mellon, Janine D. Flory, Duna Abu-amara, PTSD Systems Biology Consortium, Owen M. Wolkowitz, Rachel Yehuda, Marti Jett, Leroy Hood, Charles Marmar, and Francis J. Doyle. 2019. American Journal of Physiology: Endocrinology and Metabolism.
Polygenic risk associated with post-traumatic stress disorder onset and severity
B. Misganaw, G. Guffanti, A. Lori, D. Abu-Amara, J. D. Flory, SBPBC, S. Mueller, R. Yehuda, M. Jett, C. R. Marmar, K. J. Ressler, & F. J. Doyle III. 2019. Translational Psychiatry 9.
B. Misganaw, G. Guffanti, A. Lori, D. Abu-Amara, J. D. Flory, SBPBC, S. Mueller, R. Yehuda, M. Jett, C. R. Marmar, K. J. Ressler, & F. J. Doyle III. 2019. Translational Psychiatry 9.
Compensating for Sensor Error in the Model Predictive Control of Circadian Clock Phase
Lindsey S. Brown, Elizabeth B. Klerman, & Francis J. Doyle III. 2019. IEEE Control Systems Letters, 3 (4).
Lindsey S. Brown, Elizabeth B. Klerman, & Francis J. Doyle III. 2019. IEEE Control Systems Letters, 3 (4).
Pre-Deployment Risk Factors for PTSD in Afghanistan Veterans: A Machine Learning Approach for Analyzing Multivariate Predictors
Katharina Schultebraucks, Meng Qian, Duna Abu-Amara, Kelsey Dean, Eugene Laska, Carole Siegel, Aarti Gautam, Guia Guffanti, Rasha Hammamieh, Esther Blessing, Amit Etkin, Kerry Ressler, Francis J. Doyle III, Marti Jett, & Charles Marmar. 2019. Biological Psychiatry, 85 (10).
Katharina Schultebraucks, Meng Qian, Duna Abu-Amara, Kelsey Dean, Eugene Laska, Carole Siegel, Aarti Gautam, Guia Guffanti, Rasha Hammamieh, Esther Blessing, Amit Etkin, Kerry Ressler, Francis J. Doyle III, Marti Jett, & Charles Marmar. 2019. Biological Psychiatry, 85 (10).
A new animal model of insulin-glucose dynamics in the intraperitoneal space enhances closed-loop control performance
A. Chakrabarty, J. M. Gregory, L. M. Moore, P. E. Williams, B. Farmer, A. D. Cherrington, P. Lord, B. Shelton, D. Cohen, H. C. Zisser, F. J. Doyle III, & E. Dassau. Journal of Process Control. 2019.
A. Chakrabarty, J. M. Gregory, L. M. Moore, P. E. Williams, B. Farmer, A. D. Cherrington, P. Lord, B. Shelton, D. Cohen, H. C. Zisser, F. J. Doyle III, & E. Dassau. Journal of Process Control. 2019.
A Multivariate Bayesian Optimization Framework for Long-Term Controller Adaptation in Artificial Pancreas
D Shi, E Dassau, FJ Doyle – 2018 IEEE Conference on Decision and Control (CDC), 2018.
D Shi, E Dassau, FJ Doyle – 2018 IEEE Conference on Decision and Control (CDC), 2018.
Design and Clinical Evaluation of the Interoperable Artificial Pancreas System (iAPS): Interoperable Components with Modular Design for Progressive Artificial Pancreas Research and Developement
S. Deshpande, J. E. Pinsker, S. Zavitsanou, D. Shi, R. Tompot, M. M. Church, C. Andre, F. J. Doyle III, E. Dassau. Diabetes Technology & Therapeutics. 2018.
S. Deshpande, J. E. Pinsker, S. Zavitsanou, D. Shi, R. Tompot, M. M. Church, C. Andre, F. J. Doyle III, E. Dassau. Diabetes Technology & Therapeutics. 2018.
Pharmaceutical-based entrainment of circadian phase via nonlinear model predictive control
J. H. Abel, A. Chakrabarty, E. B. Klerman, F. J. Doyle III. Automatica. 2019.
J. H. Abel, A. Chakrabarty, E. B. Klerman, F. J. Doyle III. Automatica. 2019.
Accuracy of Wrist-Worn Activity Monitors During Common Daily Physical Activities and Types of Structured Exercise: Evaluation Study
R. K. Reddy, R. Pooni, D. P. Zaharieva, B. Senf, J. E. Youssef, E. Dassau, F. J. Doyle III, M. A. Clements, M. R. Rickels, S. R. Patton, J. R. Castle, M. C. Riddell, P. G. Jacobs. JMIR Mhealth Uhealth. 2018.
R. K. Reddy, R. Pooni, D. P. Zaharieva, B. Senf, J. E. Youssef, E. Dassau, F. J. Doyle III, M. A. Clements, M. R. Rickels, S. R. Patton, J. R. Castle, M. C. Riddell, P. G. Jacobs. JMIR Mhealth Uhealth. 2018.
Multivariate Learning Framework for Long‐Term Adaptation in the Artificial Pancreas
D Shi, E Dassau, and FJ Doyle III. Bioengineering and Translational Medicine. 2018.
D Shi, E Dassau, and FJ Doyle III. Bioengineering and Translational Medicine. 2018.
Computational and experimental insights into the circadian effects of SIRT1
P. T. Foteinou, A. Venkataraman, L. J. Francey, R. C. Anafi, J. B. Hogenesch, F. J. Doyle III. PNAS, 2018.
P. T. Foteinou, A. Venkataraman, L. J. Francey, R. C. Anafi, J. B. Hogenesch, F. J. Doyle III. PNAS, 2018.
Identifying Disease Network Dysregulation through Expression Mean, Variance, and Distribution Changes
KR Dean and FJ Doyle III. IEEE Control Systems Letters. 2018.
KR Dean and FJ Doyle III. IEEE Control Systems Letters. 2018.
Zone Model Predictive Control with Glucose- and Velocity- Dependent Control Penalty Adaptation for an Artificial Pancreas
D Shi, E Dassau, FJ Doyle – 2018 Annual American Control Conference (ACC), 2018.
D Shi, E Dassau, FJ Doyle – 2018 Annual American Control Conference (ACC), 2018.
Entrainment of circadian rhythms depends on firing rates and neuropeptide release of VIP SCN neurons
Mazuski C, Abel JH, Chen SP, Hermanstyne TO, Jones JR, Simon T, Doyle FJ, Herzog ED. Entrainment of circadian rhythms depends on firing rates and neuropeptide release of VIP SCN neurons. Neuron, 2018. doi:10.1016/j.neuron.2018.06.029
Mazuski C, Abel JH, Chen SP, Hermanstyne TO, Jones JR, Simon T, Doyle FJ, Herzog ED. Entrainment of circadian rhythms depends on firing rates and neuropeptide release of VIP SCN neurons. Neuron, 2018. doi:10.1016/j.neuron.2018.06.029
Evaluation of an Artificial Pancreas with Enhanced Model Predictive Control and a Glucose Prediction Trust Index with Unannounced Exercise
J. E. Pinkser, A. J. Laguna Sanz, J. B. Lee, M. M. Church, C. Andre, L. E. Lindsey, F. J. Doyle III, and E. Dassau. Diabetes Technology and Therapeutics, 20(7), 2018.
J. E. Pinkser, A. J. Laguna Sanz, J. B. Lee, M. M. Church, C. Andre, L. E. Lindsey, F. J. Doyle III, and E. Dassau. Diabetes Technology and Therapeutics, 20(7), 2018.
Velocity-weighting & velocity-penalty MPC of an artificial pancreas: Improved safety & performance
Ravi Gondhalekar, Eyal Dassau, Francis J. Doyle III. Automatica. 2018.
Ravi Gondhalekar, Eyal Dassau, Francis J. Doyle III. Automatica. 2018.
Body Mass Index Effect on Differing Responses to Psychological Stress in Blood Glucose Dynamics in Patients With Type 1 Diabetes
Basak Ozaslan, Stephen D. Patek, Jesse H. Grabman, Jaclyn A. Shepard, Eyal Dassau, Marc D. Breton, Yogish C. Kudva, Sue A. Brown, Ananda Basu, Jordan E. Pinsker, Francis J. Doyle, III, Linda Gonder-Frederick. Journal of Diabetes Science and Technology. 2018.
Basak Ozaslan, Stephen D. Patek, Jesse H. Grabman, Jaclyn A. Shepard, Eyal Dassau, Marc D. Breton, Yogish C. Kudva, Sue A. Brown, Ananda Basu, Jordan E. Pinsker, Francis J. Doyle, III, Linda Gonder-Frederick. Journal of Diabetes Science and Technology. 2018.
Real-Time Detection of Infusion Site Failures in a Closed-Loop Artificial Pancreas
Daniel P. Howsmon, Nihat Baysal, Bruce A. Buckingham, Gregory P. Forlenza, Trang T. Ly, David M. Maahs, Tatiana Marcal, Lindsey Towers, Eric Mauritzen, Sunil Deshpande, Lauren M. Huyett, Jordan E. Pinsker, Ravi Gondhalekar, Francis J. Doyle, III, Eyal Dassau, Juergen Hahn, and B. Wayne Bequette. Journal of Diabetes Science and Technology. 2018.
Daniel P. Howsmon, Nihat Baysal, Bruce A. Buckingham, Gregory P. Forlenza, Trang T. Ly, David M. Maahs, Tatiana Marcal, Lindsey Towers, Eric Mauritzen, Sunil Deshpande, Lauren M. Huyett, Jordan E. Pinsker, Ravi Gondhalekar, Francis J. Doyle, III, Eyal Dassau, Juergen Hahn, and B. Wayne Bequette. Journal of Diabetes Science and Technology. 2018.
Design and Clinical Evaluation of a Novel Low-Glucose Prediction Algorithm with Mini-Dose Stable Glucagon Delivery in Post-Bariatric Hypoglycemia
Laguna Sanz Alejandro J., Mulla Christopher M., Fowler Kristen M., Cloutier Emilie, Goldfine Allison B., Newswanger Brett, Cummins Martin, Deshpande Sunil, Prestrelski Steven J., Strange Poul, Zisser Howard, Doyle Francis J. III, Dassau Eyal, and Patti Mary-Elizabeth. Diabetes Technology & Therapeutics. February 2018, 20(2): 127-139.
Laguna Sanz Alejandro J., Mulla Christopher M., Fowler Kristen M., Cloutier Emilie, Goldfine Allison B., Newswanger Brett, Cummins Martin, Deshpande Sunil, Prestrelski Steven J., Strange Poul, Zisser Howard, Doyle Francis J. III, Dassau Eyal, and Patti Mary-Elizabeth. Diabetes Technology & Therapeutics. February 2018, 20(2): 127-139.
Ontogeny of circadian rhythms and synchrony in the suprachiasmatic nucleus
V Carmona-Alcocer, JH Abel, TC Sun, LR Petzold, FJ Doyle III, CL Simms, ED Herzog. “Ontogeny of circadian rhythms and synchrony in the suprachiasmatic nucleus,” Journal of Neuroscience, 2017. doi:10.1523/JNEUROSCI.2006-17.2017
V Carmona-Alcocer, JH Abel, TC Sun, LR Petzold, FJ Doyle III, CL Simms, ED Herzog. “Ontogeny of circadian rhythms and synchrony in the suprachiasmatic nucleus,” Journal of Neuroscience, 2017. doi:10.1523/JNEUROSCI.2006-17.2017
12-Week 24/7 Ambulatory Artificial Pancreas With Weekly Adaptation of Insulin Delivery Settings: Effect on Hemoglobin A1c and Hypoglycemia
Eyal Dassau, Jordan E. Pinsker, Yogish C. Kudva, Sue A. Brown, Ravi Gondhalekar, Chiara Dalla Man, Steve Patek, Michele Schiavon, Vikash Dadlani, Isuru Dasanayake, Mei Mei Church, Rickey E. Carter, Wendy C. Bevier, Lauren M. Huyett, Jonathan Hughes, Stacey Anderson, Dayu Lv, Elaine Schertz, Emma Emory, Shelly K. McCrady-Spitzer, Tyler Jean, Paige K. Bradley, Ling […]
Eyal Dassau, Jordan E. Pinsker, Yogish C. Kudva, Sue A. Brown, Ravi Gondhalekar, Chiara Dalla Man, Steve Patek, Michele Schiavon, Vikash Dadlani, Isuru Dasanayake, Mei Mei Church, Rickey E. Carter, Wendy C. Bevier, Lauren M. Huyett, Jonathan Hughes, Stacey Anderson, Dayu Lv, Elaine Schertz, Emma Emory, Shelly K. McCrady-Spitzer, Tyler Jean, Paige K. Bradley, Ling […]
Whole-genome DNA methylation status associated with clinical PTSD measures of OIF/OEF veterans
R Hammamieh, N Chakraborty, A Gautam, S Muhie, R Yang, D Donohue, R Kumar, BJ Daigle Jr, Y Zhang, DA Amara, SA Miller, S Srinivasan, J Flory, R Yehuda, L Petzold, OM Wolkowitz, SH Mellon, L Hood, FJ Doyle III, C Marmar, M Jett. “Whole-genome DNA methylation status associated with clinical PTSD measures of OIF/OEF […]
R Hammamieh, N Chakraborty, A Gautam, S Muhie, R Yang, D Donohue, R Kumar, BJ Daigle Jr, Y Zhang, DA Amara, SA Miller, S Srinivasan, J Flory, R Yehuda, L Petzold, OM Wolkowitz, SH Mellon, L Hood, FJ Doyle III, C Marmar, M Jett. “Whole-genome DNA methylation status associated with clinical PTSD measures of OIF/OEF […]
A Personalized Week-to-Week Updating Algorithm to Improve Continuous Glucose Monitoring Performance
Stamatina Zavitsanou, Joon Bok Lee, Jordan E. Pinsker, Mei Mei Church, Francis J. Doyle III, Eyal Dassau, A Personalized Week-to-Week Updating Algorithm to Improve Continuous Glucose Monitoring Performance, Journal of Diabetes Science and Technology, Accepted
Stamatina Zavitsanou, Joon Bok Lee, Jordan E. Pinsker, Mei Mei Church, Francis J. Doyle III, Eyal Dassau, A Personalized Week-to-Week Updating Algorithm to Improve Continuous Glucose Monitoring Performance, Journal of Diabetes Science and Technology, Accepted
Event-Triggered Model Predictive Control For Embedded Artificial Pancreas Systems
A. Chakrabarty, S. Zavitsanou, F. J. Doyle III, E. Dassau, “Event-Triggered Model Predictive Control For Embedded Artificial Pancreas Systems.” Preprint available, IEEE Trans. Biomedical Engineering, May 2017.
A. Chakrabarty, S. Zavitsanou, F. J. Doyle III, E. Dassau, “Event-Triggered Model Predictive Control For Embedded Artificial Pancreas Systems.” Preprint available, IEEE Trans. Biomedical Engineering, May 2017.
Intraperitoneal Insulin Delivery Provides Superior Glycemic Regulation to Subcutaneous Insulin Delivery in Model Predictive Control‐based Fully‐automated Artificial Pancreas in Patients with Type 1 Diabetes: A Pilot Study
Dassau, E., Renard, E., Place, J., Farret, A., Pelletier, M.J., Lee, J., Huyett, L.M., Chakrabarty, A., Doyle III, F.J. and Zisser, H.C. “Intraperitoneal Insulin Delivery Provides Superior Glycemic Regulation to Subcutaneous Insulin Delivery in Model Predictive Control‐based Fully‐automated Artificial Pancreas in Patients with Type 1 Diabetes: A Pilot Study.” Diabetes, Obesity and Metabolism, 2017. doi: […]
Dassau, E., Renard, E., Place, J., Farret, A., Pelletier, M.J., Lee, J., Huyett, L.M., Chakrabarty, A., Doyle III, F.J. and Zisser, H.C. “Intraperitoneal Insulin Delivery Provides Superior Glycemic Regulation to Subcutaneous Insulin Delivery in Model Predictive Control‐based Fully‐automated Artificial Pancreas in Patients with Type 1 Diabetes: A Pilot Study.” Diabetes, Obesity and Metabolism, 2017. doi: […]
Feasibility of long-term closed-loop control: a multicenter 6-month trial of 24/7 automated insulin delivery
Kovatchev, B., Cheng, P., Anderson, S.M., Pinsker, J.E., Boscari, F., Buckingham, B.A., Doyle III, F.J., Hood, K.K., Brown, S.A., Breton, M.D. and Chernavvsky, D. “Feasibility of long-term closed-loop control: a multicenter 6-month trial of 24/7 automated insulin delivery.” Diabetes Technology & Therapeutics, vol. 19, no. 1, 2017.
Kovatchev, B., Cheng, P., Anderson, S.M., Pinsker, J.E., Boscari, F., Buckingham, B.A., Doyle III, F.J., Hood, K.K., Brown, S.A., Breton, M.D. and Chernavvsky, D. “Feasibility of long-term closed-loop control: a multicenter 6-month trial of 24/7 automated insulin delivery.” Diabetes Technology & Therapeutics, vol. 19, no. 1, 2017.
An Enhanced Model Predictive Control for the Artificial Pancreas Using a Confidence Index Based on Residual Analysis of Past Predictions
A.J. Laguna-Sanz, F.J. Doyle III, and E. Dassau. “An Enhanced Model Predictive Control for the Artificial Pancreas Using a Confidence Index Based on Residual Analysis of Past Predictions.” Journal of Diabetes Science and Technology, 2016. doi: 10.1177/1932296816680632
A.J. Laguna-Sanz, F.J. Doyle III, and E. Dassau. “An Enhanced Model Predictive Control for the Artificial Pancreas Using a Confidence Index Based on Residual Analysis of Past Predictions.” Journal of Diabetes Science and Technology, 2016. doi: 10.1177/1932296816680632
A systems theoretic approach to analysis and control of mammalian circadian dynamics
J.H. Abel and F.J. Doyle III. “A systems theoretic approach to analysis and control of mammalian circadian dynamics.” Chemical Engineering Research and Design, 2016. doi:10.1016/j.cherd.2016.09.033
J.H. Abel and F.J. Doyle III. “A systems theoretic approach to analysis and control of mammalian circadian dynamics.” Chemical Engineering Research and Design, 2016. doi:10.1016/j.cherd.2016.09.033
Embedded Control in Wearable Medical Devices: Application to the Artificial Pancreas
S. Zavitsanou, A. Chakrabarty, E. Dassau, and F.J. Doyle III. “Embedded Control in Wearable Medical Devices: Application to the Artificial Pancreas.” Processes 4(4), 35, 2016. doi:10.3390/pr4040035
S. Zavitsanou, A. Chakrabarty, E. Dassau, and F.J. Doyle III. “Embedded Control in Wearable Medical Devices: Application to the Artificial Pancreas.” Processes 4(4), 35, 2016. doi:10.3390/pr4040035
Periodic zone-MPC with asymmetric costs for outpatient-ready safety of an artificial pancreas to treat type 1 diabetes.
R. Gondhalekar, E. Dassau, and F.J. Doyle III. “Periodic zone-MPC with asymmetric costs for outpatient-ready safety of an artificial pancreas to treat type 1 diabetes.” Automatica 71: 237-246, 2016. doi:10.1016/j.automatica.2016.04.015
R. Gondhalekar, E. Dassau, and F.J. Doyle III. “Periodic zone-MPC with asymmetric costs for outpatient-ready safety of an artificial pancreas to treat type 1 diabetes.” Automatica 71: 237-246, 2016. doi:10.1016/j.automatica.2016.04.015
Outcome Measures for Artificial Pancreas Clinical Trials: A Consensus Report.
D.M. Maahs, B.A. Buckingham, J.R. Castle, A. Cinar, E.R. Damiano, E. Dassau, J.H. DeVries, F.J. Doyle III, S.C. Griffen, A. Haidar, L. Heinemann, R. Hovorka, T.W. Jones, C. Kollman, B. Kovatchev, B.L. Levy, R. Nimri, D.N. O’Neal, M. Philip, E. Renard, S.J. Russell, S.A. Weinzimer, H. Zisser, J.W. Lum. Diabetes Care. 39(7):1175-9, 2016. doi: 10.2337/dc15-2716. […]
D.M. Maahs, B.A. Buckingham, J.R. Castle, A. Cinar, E.R. Damiano, E. Dassau, J.H. DeVries, F.J. Doyle III, S.C. Griffen, A. Haidar, L. Heinemann, R. Hovorka, T.W. Jones, C. Kollman, B. Kovatchev, B.L. Levy, R. Nimri, D.N. O’Neal, M. Philip, E. Renard, S.J. Russell, S.A. Weinzimer, H. Zisser, J.W. Lum. Diabetes Care. 39(7):1175-9, 2016. doi: 10.2337/dc15-2716. […]
Preliminary Evaluation of a Long-Term Intraperitoneal Glucose Sensor With Flushing Mechanism.
L.M. Huyett, R. Mittal, H.C. Zisser, E.S. Luxon, A. Yee, E. Dassau, F.J. Doyle III, D.R. Burnett. J Diabetes Sci Technol. 2016. doi:10.1177/1932296816640542
L.M. Huyett, R. Mittal, H.C. Zisser, E.S. Luxon, A. Yee, E. Dassau, F.J. Doyle III, D.R. Burnett. J Diabetes Sci Technol. 2016. doi:10.1177/1932296816640542
Randomized Crossover Comparison of Personalized MPC and PID Control Algorithms for the Artificial Pancreas.
J.E. Pinsker, J.B. Lee, E. Dassau, D.E. Seborg, P.K. Bradley, R. Gondhalekar, W.C. Bevier, L. Huyett, H.C. Zisser, F.J. Doyle III. Diabetes Care, 39(7): 1135-42, 2016. doi: 10.2337/dc15-2344.
J.E. Pinsker, J.B. Lee, E. Dassau, D.E. Seborg, P.K. Bradley, R. Gondhalekar, W.C. Bevier, L. Huyett, H.C. Zisser, F.J. Doyle III. Diabetes Care, 39(7): 1135-42, 2016. doi: 10.2337/dc15-2344.
Functional network inference of the suprachiasmatic nucleus
J.H. Abel, K. Meeker, D. Granados-Fuentes, P.C. St. John, T.J. Wang, B.B. Bales, F.J. Doyle III, E.D. Herzog, L.R. Petzold. “Functional network inference of the suprachiasmatic nucleus.” Proceedings of the National Academy of Sciences of the United States of America, 113(16), 2016. doi:10.1073/pnas.1521178113
J.H. Abel, K. Meeker, D. Granados-Fuentes, P.C. St. John, T.J. Wang, B.B. Bales, F.J. Doyle III, E.D. Herzog, L.R. Petzold. “Functional network inference of the suprachiasmatic nucleus.” Proceedings of the National Academy of Sciences of the United States of America, 113(16), 2016. doi:10.1073/pnas.1521178113
Adjustment of open-loop settings to improve closed-loop results in type 1 diabetes: a multicenter randomized trial
E. Dassau, S.A. Brown, A. Basu, J.E. Pinsker, Y.C. Kudva, R. Gondhalekar, S. Patek, D. Lv, M. Schiavon, J.B. Lee, C.D. Man, L. Hinshaw, K. Castorino, A. Mallad, V. Dadlani, S.K. McCrady-Spitzer, M. McElwee-Malloy, C.A. Wakeman, W.C. Bevier, P.K. Bradley, B. Kovatchev, C. Cobelli, H.C. Zisser, F.J. Doyle III, “Adjustment of open-loop settings to improve […]
E. Dassau, S.A. Brown, A. Basu, J.E. Pinsker, Y.C. Kudva, R. Gondhalekar, S. Patek, D. Lv, M. Schiavon, J.B. Lee, C.D. Man, L. Hinshaw, K. Castorino, A. Mallad, V. Dadlani, S.K. McCrady-Spitzer, M. McElwee-Malloy, C.A. Wakeman, W.C. Bevier, P.K. Bradley, B. Kovatchev, C. Cobelli, H.C. Zisser, F.J. Doyle III, “Adjustment of open-loop settings to improve […]
A Coupled Stochastic Model Explains Differences in Cry Knockout Behavior
J.H. Abel, L.A. Widmer, P.C. St. John, J. Stelling, and F.J. Doyle III, ” A Coupled Stochastic Model Explains Differences in Cry Knockout Behavior.” IEEE Life Sciences Letters, Jun 2015. doi:10.1109/LLS.2015.2439498
J.H. Abel, L.A. Widmer, P.C. St. John, J. Stelling, and F.J. Doyle III, ” A Coupled Stochastic Model Explains Differences in Cry Knockout Behavior.” IEEE Life Sciences Letters, Jun 2015. doi:10.1109/LLS.2015.2439498
Quantifying Stochastic Noise in Cultured Circadian Reporter Cells.
St John PC, Doyle FJ III. PLoS Comput Biol. 2015 Nov 20;11(11):e1004451. doi: 10.1371/journal.pcbi.1004451.
St John PC, Doyle FJ III. PLoS Comput Biol. 2015 Nov 20;11(11):e1004451. doi: 10.1371/journal.pcbi.1004451.
Systems biology approach to understanding post-traumatic stress disorder
G.S. Thakur, B.J. Daigle Jr, K.R. Dean, Y. Zhang, M. Rodriguez-Fernandez, R. Hammamieh, R. Yang, M. Jett, J. Palma, L.R. Petzold, F.J. Doyle III, “Systems biology approach to understanding post-traumatic stress disorder,” Molecular bioSystems, Jan 2015. [DOI]
G.S. Thakur, B.J. Daigle Jr, K.R. Dean, Y. Zhang, M. Rodriguez-Fernandez, R. Hammamieh, R. Yang, M. Jett, J. Palma, L.R. Petzold, F.J. Doyle III, “Systems biology approach to understanding post-traumatic stress disorder,” Molecular bioSystems, Jan 2015. [DOI]
Amplitude metrics for cellular circadian bioluminescence reporters
P.C. St John, S.R. Taylor, J.H. Abel, F.J. Doyle III, “Amplitude metrics for cellular circadian bioluminescence reporters,” Biophysical Journal, vol. 107, no. 11, pp. 2712-22,Dec 2014. [DOI]
P.C. St John, S.R. Taylor, J.H. Abel, F.J. Doyle III, “Amplitude metrics for cellular circadian bioluminescence reporters,” Biophysical Journal, vol. 107, no. 11, pp. 2712-22,Dec 2014. [DOI]
Closed-loop artificial pancreas systems: engineering the algorithms
F.J. Doyle III, L. M. Huyett, J. B. Lee, H. C. Zisser, E. Dassau , “Closed- Loop Artificial Pancreas Systems: Engineering the Algorithms,” Diabetes Care, May 2014. [DOI]
F.J. Doyle III, L. M. Huyett, J. B. Lee, H. C. Zisser, E. Dassau , “Closed- Loop Artificial Pancreas Systems: Engineering the Algorithms,” Diabetes Care, May 2014. [DOI]
Novel insulin delivery profiles for mixed meals for sensor-augmented pump and closed-loop artificial pancreas therapy for type 1 diabetes mellitus
A. Srinivasan, J.B. Lee, E. Dassau, F.J. Doyle III, “Novel insulin delivery profiles for mixed meals for sensor-augmented pump and closed-loop artificial pancreas therapy for type 1 diabetes mellitus,” Journal of Diabetes Science and Technology, vol. 8, no. 5, pp. 957-68,Sep 2014. [DOI]
A. Srinivasan, J.B. Lee, E. Dassau, F.J. Doyle III, “Novel insulin delivery profiles for mixed meals for sensor-augmented pump and closed-loop artificial pancreas therapy for type 1 diabetes mellitus,” Journal of Diabetes Science and Technology, vol. 8, no. 5, pp. 957-68,Sep 2014. [DOI]
Glucose sensing in the peritoneal space offers faster kinetics than sensing in the subcutaneous space
D.R. Burnett, L.M. Huyett, H.C. Zisser, F.J. Doyle III, B.D. Mensh, “Glucose sensing in the peritoneal space offers faster kinetics than sensing in the subcutaneous space,” Diabetes, vol. 63, no. 7, pp. 2498-505,Jul 2014. [DOI]
D.R. Burnett, L.M. Huyett, H.C. Zisser, F.J. Doyle III, B.D. Mensh, “Glucose sensing in the peritoneal space offers faster kinetics than sensing in the subcutaneous space,” Diabetes, vol. 63, no. 7, pp. 2498-505,Jul 2014. [DOI]
Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock
P.C. St John, T. Hirota, S.A. Kay, F.J. Doyle III, “Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock,” Proceedings of the National Academy of Sciences of the United States of America, Jan 2014. [DOI]
P.C. St John, T. Hirota, S.A. Kay, F.J. Doyle III, “Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock,” Proceedings of the National Academy of Sciences of the United States of America, Jan 2014. [DOI]
Note: Parameter-independent bounding of the stochastic Michaelis-Menten steady-state intrinsic noise variance
L.A. Widmer, J. Stelling, F.J. Doyle III, “Note: Parameter-independent bounding of the stochastic Michaelis-Menten steady-state intrinsic noise variance,” The Journal of Chemical Physics, vol. 139, no. 16, pp. 166102, Oct 2013. [DOI]
L.A. Widmer, J. Stelling, F.J. Doyle III, “Note: Parameter-independent bounding of the stochastic Michaelis-Menten steady-state intrinsic noise variance,” The Journal of Chemical Physics, vol. 139, no. 16, pp. 166102, Oct 2013. [DOI]
Modeling the Intra- and Extracellular Cytokine Signaling Pathway under Heat Stroke in the Liver
M. Rodriguez-Fernandez, B. Grosman, T.M. Yuraszeck, B.G. Helwig, L.R. Leon, F.J. Doyle III, M. Wang, “Modeling the Intra- and Extracellular Cytokine Signaling Pathway under Heat Stroke in the Liver,” PLoS ONE, vol. 8, no. 9, pp. e73393, 2013. [DOI]
M. Rodriguez-Fernandez, B. Grosman, T.M. Yuraszeck, B.G. Helwig, L.R. Leon, F.J. Doyle III, M. Wang, “Modeling the Intra- and Extracellular Cytokine Signaling Pathway under Heat Stroke in the Liver,” PLoS ONE, vol. 8, no. 9, pp. e73393, 2013. [DOI]
Statistical analysis of the pulse-coupled synchronization strategy for wireless sensor networks
Y. Q. Wang, F. Nunez, F. J. Doyle III. Statistical analysis of the pulse-coupled synchronization strategy for wireless sensor networks. IEEE Transactions on Signal Processing, In press. [DOI]
Y. Q. Wang, F. Nunez, F. J. Doyle III. Statistical analysis of the pulse-coupled synchronization strategy for wireless sensor networks. IEEE Transactions on Signal Processing, In press. [DOI]
Intercellular delay regulates the collective period of repressively coupled gene regulatory oscillator networks
Y. Q. Wang, Y. Hori, S. Hara, F. J. Doyle III. Intercellular delay regulates the collective period of repressively coupled gene regulatory oscillator networks. IEEE Transactions on Automatic Control, In press. [DOI]
Y. Q. Wang, Y. Hori, S. Hara, F. J. Doyle III. Intercellular delay regulates the collective period of repressively coupled gene regulatory oscillator networks. IEEE Transactions on Automatic Control, In press. [DOI]
Estimating confidence intervals in predicted responses for oscillatory biological models
P.C. St John, F.J. Doyle III, “Estimating confidence intervals in predicted responses for oscillatory biological models,” BMC Systems Biology, vol. 7, no. 1, pp. 71, Jul 2013. [DOI]
P.C. St John, F.J. Doyle III, “Estimating confidence intervals in predicted responses for oscillatory biological models,” BMC Systems Biology, vol. 7, no. 1, pp. 71, Jul 2013. [DOI]
Model-Based Personalization Scheme of an Artificial Pancreas for Type 1 Diabetes Applications
J. B. Lee, E. Dassau, D. Seborg, F.J. Doyle III, “Model-Based Personalization Scheme of an Artificial Pancreas for Type 1 Diabetes Applications,” Proceedings of the American Controls Conference 2013.
J. B. Lee, E. Dassau, D. Seborg, F.J. Doyle III, “Model-Based Personalization Scheme of an Artificial Pancreas for Type 1 Diabetes Applications,” Proceedings of the American Controls Conference 2013.
Increasing sync rate of pulse-coupled oscillators via phase response function design: theory and application to wireless networks
Y. Q. Wang, F. Nunez, F. J. Doyle III, “Increasing sync rate of pulse-coupled oscillators via phase response function design: theory and application to wireless networks,” IEEE Transactions on Control Systems Technology. (in press) [DOI]
Y. Q. Wang, F. Nunez, F. J. Doyle III, “Increasing sync rate of pulse-coupled oscillators via phase response function design: theory and application to wireless networks,” IEEE Transactions on Control Systems Technology. (in press) [DOI]
The influence of global and local cues on the rate of synchronization in the presence of time delays
Y. Q. Wang, F. J. Doyle III. “The influence of global and local cues on the rate of synchronization in the presence of time delays,” Automatica, (in press) [DOI]
Y. Q. Wang, F. J. Doyle III. “The influence of global and local cues on the rate of synchronization in the presence of time delays,” Automatica, (in press) [DOI]
Exponential synchronization rate of Kuramoto oscillators in the presence of a pacemaker
Y. Q. Wang, F. J. Doyle III. Exponential synchronization rate of Kuramoto oscillators in the presence of a pacemaker. IEEE Transactions on Automatic Control, 58(4)9889-994, 2013 [DOI]
Y. Q. Wang, F. J. Doyle III. Exponential synchronization rate of Kuramoto oscillators in the presence of a pacemaker. IEEE Transactions on Automatic Control, 58(4)9889-994, 2013 [DOI]
Clinical evaluation of a personalized artificial pancreas
E. Dassau, H. Zisser, R.A. Harvey, M.W. Percival, B. Grosman, W. Bevier, E. Atlas, S. Miller, R. Nimri, L. Jovanovic, F.J. Doyle III “Clinical evaluation of a personalized artificial pancreas,” Diabetes Care, vol. 36, no. 4, pp. 801-9, Apr 2013. [DOI]
E. Dassau, H. Zisser, R.A. Harvey, M.W. Percival, B. Grosman, W. Bevier, E. Atlas, S. Miller, R. Nimri, L. Jovanovic, F.J. Doyle III “Clinical evaluation of a personalized artificial pancreas,” Diabetes Care, vol. 36, no. 4, pp. 801-9, Apr 2013. [DOI]
In silico evaluation of an artificial pancreas combining exogenous ultrafast-acting technosphere insulin with zone model predictive control
J.J. Lee, E. Dassau, H. Zisser, R.A. Harvey, L. Jovanovič, F.J. Doyle III “In silico evaluation of an artificial pancreas combining exogenous ultrafast-acting technosphere insulin with zone model predictive control,” Journal of Diabetes Science and Technology, vol. 7, no. 1, pp. 215-26, January 2013. [PMID]
J.J. Lee, E. Dassau, H. Zisser, R.A. Harvey, L. Jovanovič, F.J. Doyle III “In silico evaluation of an artificial pancreas combining exogenous ultrafast-acting technosphere insulin with zone model predictive control,” Journal of Diabetes Science and Technology, vol. 7, no. 1, pp. 215-26, January 2013. [PMID]
Computational modeling of glucose transport in pancreatic β-cells identifies metabolic thresholds and therapeutic targets in diabetes
C. Luni, J.D. Marth, F.J. Doyle III, “Computational modeling of glucose transport in pancreatic β-cells identifies metabolic thresholds and therapeutic targets in diabetes,” PloS One, vol. 7, no. 12, pp. e53130, December 2012. [DOI]
C. Luni, J.D. Marth, F.J. Doyle III, “Computational modeling of glucose transport in pancreatic β-cells identifies metabolic thresholds and therapeutic targets in diabetes,” PloS One, vol. 7, no. 12, pp. e53130, December 2012. [DOI]
Design of the health monitoring system for the artificial pancreas: low glucose prediction module
R.A. Harvey, E. Dassau, H. Zisser, D.E. Seborg, L. Jovanovič, F.J. Doyle III “Design of the health monitoring system for the artificial pancreas: low glucose prediction module,” Journal of Diabetes Science and Technology, vol. 6, no. 6, pp. 1345-54, November 2012. [PMID]
R.A. Harvey, E. Dassau, H. Zisser, D.E. Seborg, L. Jovanovič, F.J. Doyle III “Design of the health monitoring system for the artificial pancreas: low glucose prediction module,” Journal of Diabetes Science and Technology, vol. 6, no. 6, pp. 1345-54, November 2012. [PMID]
Optimal phase response functions for fast pulse-coupled synchronization in wireless sensor networks
Y. Q. Wang, F. J. Doyle III. “Optimal phase response functions for fast pulse-coupled synchronization in wireless sensor networks,” IEEE Transactions on Signal Processing. vol. 60, no. 10, 2012, pp. 5583–5588, October 2012. [DOI]
Y. Q. Wang, F. J. Doyle III. “Optimal phase response functions for fast pulse-coupled synchronization in wireless sensor networks,” IEEE Transactions on Signal Processing. vol. 60, no. 10, 2012, pp. 5583–5588, October 2012. [DOI]
Energy-efficient pulse-coupled synchronization strategy design for wireless sensor networks through reduced idle listening
Y. Q. Wang, F. Nunez, F. J. Doyle III. “Energy-efficient pulse-coupled synchronization strategy design for wireless sensor networks through reduced idle listening,” IEEE Transactions on Signal Processing, vol. 60, no. 10, 2012, pp. 5293–5306, October 2012. [DOI]
Y. Q. Wang, F. Nunez, F. J. Doyle III. “Energy-efficient pulse-coupled synchronization strategy design for wireless sensor networks through reduced idle listening,” IEEE Transactions on Signal Processing, vol. 60, no. 10, 2012, pp. 5293–5306, October 2012. [DOI]
Fully integrated artificial pancreas in type 1 diabetes: modular closed-loop glucose control maintains near normoglycemia
M. Breton, A. Farret, D. Bruttomesso, S. Anderson, L. Magni, S. Patek, C. Dalla Man, J. Place, S. Demartini, S. Del Favero, C. Toffanin, C. Hughes-Karvetski, E. Dassau, H. Zisser, F.J. Doyle III, G. De Nicolao, A. Avogaro, C. Cobelli, E. Renard, B. Kovatchev, International Artificial Pancreas Study Group, “Fully integrated artificial pancreas in type […]
M. Breton, A. Farret, D. Bruttomesso, S. Anderson, L. Magni, S. Patek, C. Dalla Man, J. Place, S. Demartini, S. Del Favero, C. Toffanin, C. Hughes-Karvetski, E. Dassau, H. Zisser, F.J. Doyle III, G. De Nicolao, A. Avogaro, C. Cobelli, E. Renard, B. Kovatchev, International Artificial Pancreas Study Group, “Fully integrated artificial pancreas in type […]
Pilot studies of wearable outpatient artificial pancreas in type 1 diabetes
C. Cobelli, E. Renard, B.P. Kovatchev, P. Keith-Hynes, N. Ben Brahim, J. Place, S. Del Favero, M. Breton, A. Farret, D. Bruttomesso, E. Dassau, H. Zisser, F.J. Doyle III, S.D. Patek, A. Avogaro, “Pilot studies of wearable outpatient artificial pancreas in type 1 diabetes,” Diabetes Care, vol. 35, no. 9, pp. e65-7, Sep 2012. [DOI]
C. Cobelli, E. Renard, B.P. Kovatchev, P. Keith-Hynes, N. Ben Brahim, J. Place, S. Del Favero, M. Breton, A. Farret, D. Bruttomesso, E. Dassau, H. Zisser, F.J. Doyle III, S.D. Patek, A. Avogaro, “Pilot studies of wearable outpatient artificial pancreas in type 1 diabetes,” Diabetes Care, vol. 35, no. 9, pp. e65-7, Sep 2012. [DOI]
Clinically relevant hypoglycemia prediction metrics for event mitigation
R.A. Harvey, E. Dassau, H.C. Zisser, W. Bevier, D.E. Seborg, L. Jovanovič, F.J. Doyle III “Clinically relevant hypoglycemia prediction metrics for event mitigation,” Diabetes Technology & Therapeutics, vol. 14, no. 8, pp. 719-27, Aug 2012. [DOI]
R.A. Harvey, E. Dassau, H.C. Zisser, W. Bevier, D.E. Seborg, L. Jovanovič, F.J. Doyle III “Clinically relevant hypoglycemia prediction metrics for event mitigation,” Diabetes Technology & Therapeutics, vol. 14, no. 8, pp. 719-27, Aug 2012. [DOI]
A Detailed Modular Analysis of Heat-Shock Protein Dynamics under Acute and Chronic Stress and its Implication in Anxiety Disorders
K. Sriram, M. Rodriguez-Fernandez, F.J. Doyle III, “A Detailed Modular Analysis of Heat-Shock Protein Dynamics under Acute and Chronic Stress and its Implication in Anxiety Disorders”, PLoS ONE, vol. 7, no. 8, e42958, August 2012. [DOI]
K. Sriram, M. Rodriguez-Fernandez, F.J. Doyle III, “A Detailed Modular Analysis of Heat-Shock Protein Dynamics under Acute and Chronic Stress and its Implication in Anxiety Disorders”, PLoS ONE, vol. 7, no. 8, e42958, August 2012. [DOI]
Identification of small molecule activators of cryptochrome
T. Hirota, J.W. Lee, P.C St. John, M. Sawa, K. Iwaisako, T. Noguchi, P.Y. Pongsawakul, T. Sontag, D.K. Welsh, D.A. Brenner, F.J. Doyle III, P.G. Schultz, S.A. Kay, “Identification of small molecule activators of cryptochrome,” Science, vol. 337, no. 6098, pp. 1094-1097, July 2012. [DOI]
T. Hirota, J.W. Lee, P.C St. John, M. Sawa, K. Iwaisako, T. Noguchi, P.Y. Pongsawakul, T. Sontag, D.K. Welsh, D.A. Brenner, F.J. Doyle III, P.G. Schultz, S.A. Kay, “Identification of small molecule activators of cryptochrome,” Science, vol. 337, no. 6098, pp. 1094-1097, July 2012. [DOI]
Control-relevant models for glucose control using a priori patient characteristics
K. van Heusden, E. Dassau, H.C. Zisser, D.E. Seborg, F.J. Doyle III, “Control-relevant models for glucose control using a priori patient characteristics,” IEEE Transactions on Bio-medical Engineering, vol. 59, no. 7, pp. 1839-49, Jul 2012. [DOI]
K. van Heusden, E. Dassau, H.C. Zisser, D.E. Seborg, F.J. Doyle III, “Control-relevant models for glucose control using a priori patient characteristics,” IEEE Transactions on Bio-medical Engineering, vol. 59, no. 7, pp. 1839-49, Jul 2012. [DOI]
Novel global sensitivity analysis methodology accounting for the crucial role of the distribution of input parameters: application to systems biology models
M. Rodriguez-Fernandez, J.R. Banga, F.J. Doyle III, “Novel global sensitivity analysis methodology accounting for the crucial role of the distribution of input parameters: application to systems biology models”, International Journal of Robust and Nonlinear Control, vol. 22, no. 10, pp. 1082–1102, July 2012. [DOI]
M. Rodriguez-Fernandez, J.R. Banga, F.J. Doyle III, “Novel global sensitivity analysis methodology accounting for the crucial role of the distribution of input parameters: application to systems biology models”, International Journal of Robust and Nonlinear Control, vol. 22, no. 10, pp. 1082–1102, July 2012. [DOI]
Predicting subcutaneous glucose concentration using a latent-variable-based statistical method for type 1 diabetes mellitus
C. Zhao, E. Dassau, L. Jovanovič, H.C. Zisser, F.J. Doyle III, D.E. Seborg, “Predicting subcutaneous glucose concentration using a latent-variable-based statistical method for type 1 diabetes mellitus,” Journal of Diabetes Science and Technology, vol. 6, no. 3, pp. 617-33, May 2012. [PMID]
C. Zhao, E. Dassau, L. Jovanovič, H.C. Zisser, F.J. Doyle III, D.E. Seborg, “Predicting subcutaneous glucose concentration using a latent-variable-based statistical method for type 1 diabetes mellitus,” Journal of Diabetes Science and Technology, vol. 6, no. 3, pp. 617-33, May 2012. [PMID]
Modeling Cortisol Dynamics in the Neuro-endocrine Axis Distinguishes Normal, Depression, and Post-traumatic Stress Disorder (PTSD) in Humans
K. Sriram, M. Rodriguez-Fernandez, F.J. Doyle III, “Modeling Cortisol Dynamics in the Neuro-endocrine Axis Distinguishes Normal, Depression, and Post-traumatic Stress Disorder (PTSD) in Humans”, PLoS Computational Biology, vol. 8, no. 2, e1002379, February 2012. [DOI]
K. Sriram, M. Rodriguez-Fernandez, F.J. Doyle III, “Modeling Cortisol Dynamics in the Neuro-endocrine Axis Distinguishes Normal, Depression, and Post-traumatic Stress Disorder (PTSD) in Humans”, PLoS Computational Biology, vol. 8, no. 2, e1002379, February 2012. [DOI]
Robust multi-drug therapy design and application to insulin resistance in type 2 diabetes
C. Luni, F.J. Doyle III “Robust multi-drug therapy design and application to insulin resistance in type 2 diabetes,” International Journal of Robust and Nonlinear Control, vol.21, pp.1730–1741, October 2011. [DOI]
C. Luni, F.J. Doyle III “Robust multi-drug therapy design and application to insulin resistance in type 2 diabetes,” International Journal of Robust and Nonlinear Control, vol.21, pp.1730–1741, October 2011. [DOI]
Effects of light dynamics on coral spawning synchrony
C.A. Boch, B. Ananthasubramaniam, A. Sweeney, F.J. Doyle III, D.E. Morse “Effects of light dynamics on coral spawning synchrony,” Biological Bulletin, vol. 220, pp. 161–173, June 2011. [DOI]
C.A. Boch, B. Ananthasubramaniam, A. Sweeney, F.J. Doyle III, D.E. Morse “Effects of light dynamics on coral spawning synchrony,” Biological Bulletin, vol. 220, pp. 161–173, June 2011. [DOI]
On influences of global and local cues on the rate of synchronization of oscillator networks
Y.Q. Wang, F.J. Doyle III “On influences of global and local cues on the rate of synchronization of oscillator networks,” Automatica, vol. 47, no. 6, June 2011. [DOI]
Y.Q. Wang, F.J. Doyle III “On influences of global and local cues on the rate of synchronization of oscillator networks,” Automatica, vol. 47, no. 6, June 2011. [DOI]
Development of a multi-parametric model predictive control algorithm for insulin delivery in type 1 diabetes mellitus using clinical parameters
M.W. Percival, Y. Wang, B. Grosman, E. Dassau, H. Zisser, L. Jovanovič, F.J. Doyle III, “Development of a multi-parametric model predictive control algorithm for insulin delivery in type 1 diabetes mellitus using clinical parameters,” Journal of Process Control, vol. 21, no. 3, pp. 391-404, Mar 2011. [DOI]
M.W. Percival, Y. Wang, B. Grosman, E. Dassau, H. Zisser, L. Jovanovič, F.J. Doyle III, “Development of a multi-parametric model predictive control algorithm for insulin delivery in type 1 diabetes mellitus using clinical parameters,” Journal of Process Control, vol. 21, no. 3, pp. 391-404, Mar 2011. [DOI]
Integrate-and-fire models of insolation-driven entrainment of broadcast spawning in corals
B. Ananthasubramaniam, R.M. Nisbet, D.E. Morse, F.J. Doyle III, “Integrate-and-fire models of insolation-driven entrainment of broadcast spawning in corals ,” Theoretical Ecology, vol. 4, no. 1, pp. 69–85, February 2011. [DOI]
B. Ananthasubramaniam, R.M. Nisbet, D.E. Morse, F.J. Doyle III, “Integrate-and-fire models of insolation-driven entrainment of broadcast spawning in corals ,” Theoretical Ecology, vol. 4, no. 1, pp. 69–85, February 2011. [DOI]
Distribution-based sensitivity metric for highly variable biochemical systems
H.P. Mirsky, S.R. Taylor, R.A. Harvey, J. Stelling, F.J. Doyle III “Distribution-based sensitivity metric for highly variable biochemical systems,” IET Systems Biology, vol. 5, no. 1, pp. 50, Jan 2011. [DOI]
H.P. Mirsky, S.R. Taylor, R.A. Harvey, J. Stelling, F.J. Doyle III “Distribution-based sensitivity metric for highly variable biochemical systems,” IET Systems Biology, vol. 5, no. 1, pp. 50, Jan 2011. [DOI]
Vulnerabilities in the Tau Network and the Role of Ultrasensitive Points in Tau Pathophysiology
T.M Yuraszeck, P. Neveu, M. Rodriguez, A. Robinson, K.S. Kosik, F.J. Doyle III “Vulnerabilities in the Tau Network and the Role of Ultrasensitive Points in Tau Pathophysiology,” PLoS Comput Biol, vol. 6, no. 11, November 2010. [DOI]
T.M Yuraszeck, P. Neveu, M. Rodriguez, A. Robinson, K.S. Kosik, F.J. Doyle III “Vulnerabilities in the Tau Network and the Role of Ultrasensitive Points in Tau Pathophysiology,” PLoS Comput Biol, vol. 6, no. 11, November 2010. [DOI]
Confidence from uncertainty – A multi-target drug screening method from robust control theory
C. Luni, J.E. Shoemaker, K.R. Sanft, L.R. Petzold, F.J. Doyle III, “Confidence from uncertainty – A multi-target drug screening method from robust control theory,” BMC Systems Biology, vol. 4, no. 1, pp. 161, November 2010. [DOI]
C. Luni, J.E. Shoemaker, K.R. Sanft, L.R. Petzold, F.J. Doyle III, “Confidence from uncertainty – A multi-target drug screening method from robust control theory,” BMC Systems Biology, vol. 4, no. 1, pp. 161, November 2010. [DOI]
Cell population modeling describes intrinsic heterogeneity: hematopoietic stem cells, a case study
C. Luni, F.J. Doyle III, N. Elvassore, “Cell population modeling describes intrinsic heterogeneity: hematopoietic stem cells, a case study,” IET Systems Biology, vol. 4, no. 161, November 2010. [DOI]
C. Luni, F.J. Doyle III, N. Elvassore, “Cell population modeling describes intrinsic heterogeneity: hematopoietic stem cells, a case study,” IET Systems Biology, vol. 4, no. 161, November 2010. [DOI]
Automatic bolus and adaptive basal algorithm for the artificial pancreatic β-cell
Y. Wang, E. Dassau, H. Zisser, L. Jovanovič, F.J. Doyle III, “Automatic bolus and adaptive basal algorithm for the artificial pancreatic β-cell,” Diabetes Technology & Therapeutics, vol. 12, no. 11, pp. 879-87, Nov 2010. [DOI]
Y. Wang, E. Dassau, H. Zisser, L. Jovanovič, F.J. Doyle III, “Automatic bolus and adaptive basal algorithm for the artificial pancreatic β-cell,” Diabetes Technology & Therapeutics, vol. 12, no. 11, pp. 879-87, Nov 2010. [DOI]
Quest for the artificial pancreas: combining technology with treatment
R.A. Harvey, Y. Wang, B. Grosman, M.W. Percival, W. Bevier, D.A. Finan, H. Zisser, D.E. Seborg, L. Jovanovic, F.J. Doyle III, E. Dassau “Quest for the artificial pancreas: combining technology with treatment,” IEEE Engineering in Medicine and Biology Magazine : The Quarterly Magazine of the Engineering in Medicine & Biology Society, vol. 29, no. 2, […]
R.A. Harvey, Y. Wang, B. Grosman, M.W. Percival, W. Bevier, D.A. Finan, H. Zisser, D.E. Seborg, L. Jovanovic, F.J. Doyle III, E. Dassau “Quest for the artificial pancreas: combining technology with treatment,” IEEE Engineering in Medicine and Biology Magazine : The Quarterly Magazine of the Engineering in Medicine & Biology Society, vol. 29, no. 2, […]
Zone-Model Predictive Control: A Strategy to Minimize Hyper- and Hypo-glycemic Events
B. Grosman, E. Dassau, H. Zisser, L. Jovanovic, F.J. Doyle III, “Zone-Model Predictive Control: A Strategy to Minimize Hyper- and Hypo-glycemic Events,” J Diabetes Sci Technol, vol. 4, no. 4, pp. 961–975, July 2010. [DOI]
B. Grosman, E. Dassau, H. Zisser, L. Jovanovic, F.J. Doyle III, “Zone-Model Predictive Control: A Strategy to Minimize Hyper- and Hypo-glycemic Events,” J Diabetes Sci Technol, vol. 4, no. 4, pp. 961–975, July 2010. [DOI]
An advisory protocol for rapid- and slow-acting insulin therapy based on a run-to-run methodology
F. Campos-Cornejo, D.U. Campos-Delgado, D. Espinoza-Trejo, H. Zisser, L. Jovanovic, F.J. Doyle III, E. Dassau, “An advisory protocol for rapid- and slow-acting insulin therapy based on a run-to-run methodology,” Diabetes Technology & Therapeutics, vol. 12, no. 7, pp. 555-65, Jul 2010. [DOI]
F. Campos-Cornejo, D.U. Campos-Delgado, D. Espinoza-Trejo, H. Zisser, L. Jovanovic, F.J. Doyle III, E. Dassau, “An advisory protocol for rapid- and slow-acting insulin therapy based on a run-to-run methodology,” Diabetes Technology & Therapeutics, vol. 12, no. 7, pp. 555-65, Jul 2010. [DOI]
Zone model predictive control: a strategy to minimize hyper- and hypoglycemic events
B. Grosman, E. Dassau, H.C. Zisser, L. Jovanovic, F.J. Doyle III, “Zone model predictive control: a strategy to minimize hyper- and hypoglycemic events,” Journal of Diabetes Science and Technology, vol. 4, no. 4, pp. 961-75, Jul 2010. [PMID]
B. Grosman, E. Dassau, H.C. Zisser, L. Jovanovic, F.J. Doyle III, “Zone model predictive control: a strategy to minimize hyper- and hypoglycemic events,” Journal of Diabetes Science and Technology, vol. 4, no. 4, pp. 961-75, Jul 2010. [PMID]
Proposed clinical application for tuning fuzzy logic controller of artificial pancreas utilizing a personalization factor
R. Mauseth, Y. Wang, E. Dassau, R. Kircher Jr, D. Matheson, H. Zisser, L. Jovanovic, F.J. Doyle III, “Proposed clinical application for tuning fuzzy logic controller of artificial pancreas utilizing a personalization factor,” Journal of Diabetes Science and Technology, vol. 4, no. 4, pp. 913-22, Jul 2010. [PMID]
R. Mauseth, Y. Wang, E. Dassau, R. Kircher Jr, D. Matheson, H. Zisser, L. Jovanovic, F.J. Doyle III, “Proposed clinical application for tuning fuzzy logic controller of artificial pancreas utilizing a personalization factor,” Journal of Diabetes Science and Technology, vol. 4, no. 4, pp. 913-22, Jul 2010. [PMID]
Fathead Minnow Steroidogenesis: in silico Analyses Reveals Tradeoffs Between Nominal Target Efficacy and Robustness to Cross-talk
J.E. Shoemaker, K. Gayen, N. Garcia-Reyero, E.J. Perkins, D.L. Villeneuve, L. Liu, F.J. Doyle III, “Fathead Minnow Steroidogenesis: in silico Analyses Reveals Tradeoffs Between Nominal Target Efficacy and Robustness to Cross-talk,” BMC Systems Biology, June 2010.[DOI]
J.E. Shoemaker, K. Gayen, N. Garcia-Reyero, E.J. Perkins, D.L. Villeneuve, L. Liu, F.J. Doyle III, “Fathead Minnow Steroidogenesis: in silico Analyses Reveals Tradeoffs Between Nominal Target Efficacy and Robustness to Cross-talk,” BMC Systems Biology, June 2010.[DOI]
Real-Time Hypoglycemia Prediction Suite Using Continuous Glucose Monitoring: A safety net for the artificial pancreas
E. Dassau, F. Cameron, H. Lee, B.W. Bequette, H. Zisser, L. Jovanovic, H.P. Chase, D.M. Wilson, B.A. Buckingham, F.J. Doyle III, “Real-Time Hypoglycemia Prediction Suite Using Continuous Glucose Monitoring: A safety net for the artificial pancreas,” Diabetes Care, vol. 33, no. 6, pp. 1013–1017, June 2010. [DOI]
E. Dassau, F. Cameron, H. Lee, B.W. Bequette, H. Zisser, L. Jovanovic, H.P. Chase, D.M. Wilson, B.A. Buckingham, F.J. Doyle III, “Real-Time Hypoglycemia Prediction Suite Using Continuous Glucose Monitoring: A safety net for the artificial pancreas,” Diabetes Care, vol. 33, no. 6, pp. 1013–1017, June 2010. [DOI]
Model Predictive Control with Learning-Type Set-point:Application to Artificial Pancreatic β-Cell
Y. Wang, H. Zisser, E. Dassau, L. Jovanovic, F.J. Doyle III, “Model Predictive Control with Learning-Type Set-point:Application to Artificial Pancreatic β-Cell ,” AIChE Journal, vol. 56, no. 6, pp. 1510–1518, June 2010.[DOI]
Y. Wang, H. Zisser, E. Dassau, L. Jovanovic, F.J. Doyle III, “Model Predictive Control with Learning-Type Set-point:Application to Artificial Pancreatic β-Cell ,” AIChE Journal, vol. 56, no. 6, pp. 1510–1518, June 2010.[DOI]
Prevention of Nocturnal Hypoglycemia Using Predictive Alarm Algorithms and Insulin Pump Suspension
B.A. Buckingham, H.P. Chase, E. Dassau, E. Corby, P. Clinton, V. Gage, K. Caswell, J. Wilkinson, F. Cameron, H. Lee, B.W. Bequette, F.J. Doyle III, “Prevention of Nocturnal Hypoglycemia Using Predictive Alarm Algorithms and Insulin Pump Suspension,” Diabetes Care, vol. 33, no. 5, pp. 1013–1017, May 2010.[DOI]
B.A. Buckingham, H.P. Chase, E. Dassau, E. Corby, P. Clinton, V. Gage, K. Caswell, J. Wilkinson, F. Cameron, H. Lee, B.W. Bequette, F.J. Doyle III, “Prevention of Nocturnal Hypoglycemia Using Predictive Alarm Algorithms and Insulin Pump Suspension,” Diabetes Care, vol. 33, no. 5, pp. 1013–1017, May 2010.[DOI]
Velocity Response Curves Support the Role of Continuous Entrainment in Circadian Clocks
S.R. Taylor, A.B. Webb, K.S. Smith, L.R. Petzold, F.J. Doyle III, “Velocity Response Curves Support the Role of Continuous Entrainment in Circadian Clocks,” J Biol Rhythms, vol. 25, no. 2, pp. 138–149, April 2010.[DOI]
S.R. Taylor, A.B. Webb, K.S. Smith, L.R. Petzold, F.J. Doyle III, “Velocity Response Curves Support the Role of Continuous Entrainment in Circadian Clocks,” J Biol Rhythms, vol. 25, no. 2, pp. 138–149, April 2010.[DOI]
Closed-Loop Control of Artificial Pancreatic β-Cell in Type 1 Diabetes Mellitus Using Model Predictive Iterative Learning Control
Y. Wang, E. Dassau, F.J. Doyle III, “Closed-Loop Control of Artificial Pancreatic β-Cell in Type 1 Diabetes Mellitus Using Model Predictive Iterative Learning Control,” Biomedical Engineering, IEEE Transactions on, vol. 57, no. 2, pp. 211–219, February 2010.[DOI]
Y. Wang, E. Dassau, F.J. Doyle III, “Closed-Loop Control of Artificial Pancreatic β-Cell in Type 1 Diabetes Mellitus Using Model Predictive Iterative Learning Control,” Biomedical Engineering, IEEE Transactions on, vol. 57, no. 2, pp. 211–219, February 2010.[DOI]
Survey on Iterative Learning Control, Repetitive Control, and Run-to-Run Control
Y. Wang, F. Gao, F.J. Doyle III, “Survey on Iterative Learning Control, Repetitive Control, and Run-to-Run Control,” J Proc Cont, vol. 19, no. 10, pp. 1589–1600, December 2009.[DOI]
Y. Wang, F. Gao, F.J. Doyle III, “Survey on Iterative Learning Control, Repetitive Control, and Run-to-Run Control,” J Proc Cont, vol. 19, no. 10, pp. 1589–1600, December 2009.[DOI]
Enhanced 911/global position system wizard: a telemedicine application for the prevention of severe hypoglycemia–monitor, alert, and locate
E. Dassau, L. Jovanovic, F.J. Doyle III, H.C. Zisser, “Enhanced 911/global position system wizard: a telemedicine application for the prevention of severe hypoglycemia–monitor, alert, and locate,” Journal of Diabetes Science and Technology, vol. 3, no. 6, pp. 1501-6, Nov 2009. [PMID]
E. Dassau, L. Jovanovic, F.J. Doyle III, H.C. Zisser, “Enhanced 911/global position system wizard: a telemedicine application for the prevention of severe hypoglycemia–monitor, alert, and locate,” Journal of Diabetes Science and Technology, vol. 3, no. 6, pp. 1501-6, Nov 2009. [PMID]
A Novel Adaptive Basal Therapy Based on the Value and Rate of Change of Blood Glucose
Y. Wang, M.W. Percival, E. Dassau, H.C. Zisser, L. Jovanovic, F.J. Doyle III, “A Novel Adaptive Basal Therapy Based on the Value and Rate of Change of Blood Glucose,” J Diabetes Sci Technol, vol. 3, pp. 1099–1108, September 2009.[DOI]
Y. Wang, M.W. Percival, E. Dassau, H.C. Zisser, L. Jovanovic, F.J. Doyle III, “A Novel Adaptive Basal Therapy Based on the Value and Rate of Change of Blood Glucose,” J Diabetes Sci Technol, vol. 3, pp. 1099–1108, September 2009.[DOI]
A model of the cell-autonomous mammalian circadian clock
H. P. Mirsky, A. C. Liu, D. K. Welsh, S. A. Kay, and F. J. Doyle III, “A model of the cell-autonomous mammalian circadian clock,” Proc Natl Acad Sci USA, vol. 106, pp. 11107–11112, June 2009.[DOI]
H. P. Mirsky, A. C. Liu, D. K. Welsh, S. A. Kay, and F. J. Doyle III, “A model of the cell-autonomous mammalian circadian clock,” Proc Natl Acad Sci USA, vol. 106, pp. 11107–11112, June 2009.[DOI]
Safety constraints in an artificial pancreatic beta cell: an implementation of model predictive control with insulin on board
C. Ellingsen, E. Dassau, H. Zisser, B. Grosman, M.W. Percival, L. Jovanovic, F.J. Doyle III, “Safety constraints in an artificial pancreatic beta cell: an implementation of model predictive control with insulin on board,” Journal of Diabetes Science and Technology, vol. 3, no. 3, pp. 536-44, May 2009. [PMID]
C. Ellingsen, E. Dassau, H. Zisser, B. Grosman, M.W. Percival, L. Jovanovic, F.J. Doyle III, “Safety constraints in an artificial pancreatic beta cell: an implementation of model predictive control with insulin on board,” Journal of Diabetes Science and Technology, vol. 3, no. 3, pp. 536-44, May 2009. [PMID]
Practical approach to design and implementation of a control algorithm in an artificial pancreatic β-cell
M. W. Percival, E. Dassau, H. Zisser, L. Jovanovic, and F. J. Doyle III, “Practical approach to design and implementation of a control algorithm in an artificial pancreatic β-cell,” Ind Eng Chem Res, vol. 48, pp. 6059–6067, April 2009.[DOI]
M. W. Percival, E. Dassau, H. Zisser, L. Jovanovic, and F. J. Doyle III, “Practical approach to design and implementation of a control algorithm in an artificial pancreatic β-cell,” Ind Eng Chem Res, vol. 48, pp. 6059–6067, April 2009.[DOI]
In silico evaluation platform for artificial pancreatic beta-cell development–a dynamic simulator for closed-loop control with hardware-in-the-loop
E. Dassau, C.C. Palerm, H. Zisser, B.A. Buckingham, L. Jovanovic, F.J. Doyle III, “In silico evaluation platform for artificial pancreatic beta-cell development–a dynamic simulator for closed-loop control with hardware-in-the-loop,” Diabetes Technology & Therapeutics, vol. 11, no. 3, pp. 187-94, Mar 2009. [DOI]
E. Dassau, C.C. Palerm, H. Zisser, B.A. Buckingham, L. Jovanovic, F.J. Doyle III, “In silico evaluation platform for artificial pancreatic beta-cell development–a dynamic simulator for closed-loop control with hardware-in-the-loop,” Diabetes Technology & Therapeutics, vol. 11, no. 3, pp. 187-94, Mar 2009. [DOI]
In silico preclinical trials: methodology and engineering guide to closed-loop control in type 1 diabetes mellitus
S.D. Patek, B.W. Bequette, M. Breton, B.A. Buckingham, E. Dassau, F.J. Doyle III, J. Lum, L. Magni, H. Zisser, “In silico preclinical trials: methodology and engineering guide to closed-loop control in type 1 diabetes mellitus,” Journal of Diabetes Science and Technology, vol. 3, no. 2, pp. 269-82, Mar 2009. [PMID]
S.D. Patek, B.W. Bequette, M. Breton, B.A. Buckingham, E. Dassau, F.J. Doyle III, J. Lum, L. Magni, H. Zisser, “In silico preclinical trials: methodology and engineering guide to closed-loop control in type 1 diabetes mellitus,” Journal of Diabetes Science and Technology, vol. 3, no. 2, pp. 269-82, Mar 2009. [PMID]
Identification of models for control of wet granulation
C. F. W. Sanders, M. J. Hounslow, and F. J. Doyle III, “Identification of models for control of wet granulation,” Powder Technology, vol. 188, pp. 255–263, January 2009.[DOI]
C. F. W. Sanders, M. J. Hounslow, and F. J. Doyle III, “Identification of models for control of wet granulation,” Powder Technology, vol. 188, pp. 255–263, January 2009.[DOI]
Coordinated basal-bolus infusion for tighter postprandial glucose control in insulin pump therapy
J. Bondia, E. Dassau, H. Zisser, R. Calm, J. Vehí, L. Jovanovič, F.J. Doyle III “Coordinated basal-bolus infusion for tighter postprandial glucose control in insulin pump therapy,” Journal of Diabetes Science and Technology, vol. 3, no. 1, pp. 89-97, Jan 2009. [PMID]
J. Bondia, E. Dassau, H. Zisser, R. Calm, J. Vehí, L. Jovanovič, F.J. Doyle III “Coordinated basal-bolus infusion for tighter postprandial glucose control in insulin pump therapy,” Journal of Diabetes Science and Technology, vol. 3, no. 1, pp. 89-97, Jan 2009. [PMID]
Experimental studies on distributions of granule size, binder content and porosity in batch drum granulation: Inferences on process modelling requirements and process sensitivities
R. Ramachandran, J. M. H. Poon, C. F. W. Sanders, T. Glaser, C. D. Immanuel, F. J. Doyle III, J. D. Litster, F. Stepanek, F.-Y. Wang, and I. T. Cameron, “Experimental studies on distributions of granule size, binder content and porosity in batch drum granulation: Inferences on process modelling requirements and process sensitivities,” Powder Technology, […]
R. Ramachandran, J. M. H. Poon, C. F. W. Sanders, T. Glaser, C. D. Immanuel, F. J. Doyle III, J. D. Litster, F. Stepanek, F.-Y. Wang, and I. T. Cameron, “Experimental studies on distributions of granule size, binder content and porosity in batch drum granulation: Inferences on process modelling requirements and process sensitivities,” Powder Technology, […]
Batch-to-batch control of characteristic points on the PSD in experimental emulsion polymerization
M. T. Dokucu and F. J. Doyle III, “Batch-to-batch control of characteristic points on the PSD in experimental emulsion polymerization,” AIChE Journal, vol. 54, pp. 3171–3187, December 2008.[DOI]
M. T. Dokucu and F. J. Doyle III, “Batch-to-batch control of characteristic points on the PSD in experimental emulsion polymerization,” AIChE Journal, vol. 54, pp. 3171–3187, December 2008.[DOI]
Bolus calculator: a review of four “smart” insulin pumps
H. Zisser, L. Robinson, W. Bevier, E. Dassau, C. Ellingsen, F.J. Doyle III, L. Jovanovic, “Bolus calculator: a review of four “smart” insulin pumps,” Diabetes Technology & Therapeutics, vol. 10, no. 6, pp. 441-4, Dec 2008. [DOI]
H. Zisser, L. Robinson, W. Bevier, E. Dassau, C. Ellingsen, F.J. Doyle III, L. Jovanovic, “Bolus calculator: a review of four “smart” insulin pumps,” Diabetes Technology & Therapeutics, vol. 10, no. 6, pp. 441-4, Dec 2008. [DOI]
A Top-Down Approach to Mechanistic Biological Modeling: Application to the Single-Chain Antibody Folding Pathway
S. Hildebrandt, D. Raden, L. Petzold, A. S. Robinson, and F. J. Doyle III, “A Top-Down Approach to Mechanistic Biological Modeling: Application to the Single-Chain Antibody Folding Pathway,” vol. 95, pp. 3535–3558, October 2008.[DOI]
S. Hildebrandt, D. Raden, L. Petzold, A. S. Robinson, and F. J. Doyle III, “A Top-Down Approach to Mechanistic Biological Modeling: Application to the Single-Chain Antibody Folding Pathway,” vol. 95, pp. 3535–3558, October 2008.[DOI]
Modular artificial beta-cell system: a prototype for clinical research
E. Dassau, H. Zisser, C. C Palerm, B. A Buckingham, L. Jovanovic, F. J Doyle III, “Modular artificial beta-cell system: a prototype for clinical research,” Journal of Diabetes Science and Technology, vol. 2, no. 5, pp. 863-72, Sep 2008. [PMID]
E. Dassau, H. Zisser, C. C Palerm, B. A Buckingham, L. Jovanovic, F. J Doyle III, “Modular artificial beta-cell system: a prototype for clinical research,” Journal of Diabetes Science and Technology, vol. 2, no. 5, pp. 863-72, Sep 2008. [PMID]
Synchrony and entrainment properties of robust circadian oscillators
N. Bagheri, S. R. Taylor, K. Meeker, L. R. Petzold, and F. J. Doyle III, “Synchrony and entrainment properties of robust circadian oscillators,” J R Soc Interface, vol. 5 Suppl 1, pp. S17-28–S17-28, August 2008.[DOI]
N. Bagheri, S. R. Taylor, K. Meeker, L. R. Petzold, and F. J. Doyle III, “Synchrony and entrainment properties of robust circadian oscillators,” J R Soc Interface, vol. 5 Suppl 1, pp. S17-28–S17-28, August 2008.[DOI]
Circadian Phase Resetting via Single and Multiple Control Targets
N. Bagheri, J. Stelling, and F. J. Doyle III, “Circadian Phase Resetting via Single and Multiple Control Targets,” PLoS Comput Biol, vol. 4, pp. e1000104–e1000104, July 2008.[DOI]
N. Bagheri, J. Stelling, and F. J. Doyle III, “Circadian Phase Resetting via Single and Multiple Control Targets,” PLoS Comput Biol, vol. 4, pp. e1000104–e1000104, July 2008.[DOI]
Closed-loop control and advisory mode evaluation of an artificial pancreatic β-cell: use of proportional-integral-derivative equivalent model-based controllers
M. W. Percival, H. Zisser, L. Jovanovic, and F. J. Doyle III, “Closed-loop control and advisory mode evaluation of an artificial pancreatic β-cell: use of proportional-integral-derivative equivalent model-based controllers,” J Diabetes Sci Technol, vol. 2, pp. 636–644, July 2008.[DOI]
M. W. Percival, H. Zisser, L. Jovanovic, and F. J. Doyle III, “Closed-loop control and advisory mode evaluation of an artificial pancreatic β-cell: use of proportional-integral-derivative equivalent model-based controllers,” J Diabetes Sci Technol, vol. 2, pp. 636–644, July 2008.[DOI]
A three-dimensional population balance model of granulation with a mechanistic representation of the nucleation and aggregation phenomena
J. M. H. Poon, C. D. Immanuel, F. J. Doyle III, and J. D. Litster, “A three-dimensional population balance model of granulation with a mechanistic representation of the nucleation and aggregation phenomena,” Chemical Engineering Science, vol. 63, pp. 1315–1329, March 2008.[DOI]
J. M. H. Poon, C. D. Immanuel, F. J. Doyle III, and J. D. Litster, “A three-dimensional population balance model of granulation with a mechanistic representation of the nucleation and aggregation phenomena,” Chemical Engineering Science, vol. 63, pp. 1315–1329, March 2008.[DOI]
Reduced-order methodologies for feedback control of particle size distribution in semi-batch emulsion copolymerization
M. T. Dokucu, M.-J. Park, and F. J. Doyle III, “Reduced-order methodologies for feedback control of particle size distribution in semi-batch emulsion copolymerization,” Chemical Engineering Science, vol. 63, pp. 1230–1245, March 2008.[DOI]
M. T. Dokucu, M.-J. Park, and F. J. Doyle III, “Reduced-order methodologies for feedback control of particle size distribution in semi-batch emulsion copolymerization,” Chemical Engineering Science, vol. 63, pp. 1230–1245, March 2008.[DOI]
A Run-to-Run Control Strategy to Adjust Basal Insulin Infusion Rates in Type 1 Diabetes
C. C. Palerm, H. Zisser, L. Jovanovi, and F. J. Doyle III, “A Run-to-Run Control Strategy to Adjust Basal Insulin Infusion Rates in Type 1 Diabetes,” J Process Control, vol. 18, pp. 258–265, March 2008. [DOI]
C. C. Palerm, H. Zisser, L. Jovanovi, and F. J. Doyle III, “A Run-to-Run Control Strategy to Adjust Basal Insulin Infusion Rates in Type 1 Diabetes,” J Process Control, vol. 18, pp. 258–265, March 2008. [DOI]
A two-level discretisation algorithm for the efficient solution of higher-dimensional population balance models
M. A. Pinto, C. D. Immanuel, and F. J. Doyle III, “A two-level discretisation algorithm for the efficient solution of higher-dimensional population balance models,” Chemical Engineering Science, vol. 63, pp. 1304–1314, March 2008.[DOI]
M. A. Pinto, C. D. Immanuel, and F. J. Doyle III, “A two-level discretisation algorithm for the efficient solution of higher-dimensional population balance models,” Chemical Engineering Science, vol. 63, pp. 1304–1314, March 2008.[DOI]
Detection of a Meal Using Continuous Glucose Monitoring: Implications for an artificial β-cell
E. Dassau, B. W. Bequette, B. A. Buckingham, and F. J. Doyle III, “Detection of a Meal Using Continuous Glucose Monitoring: Implications for an artificial β-cell,” Diabetes Care, vol. 31, pp. 295–300, February 2008.[DOI]
E. Dassau, B. W. Bequette, B. A. Buckingham, and F. J. Doyle III, “Detection of a Meal Using Continuous Glucose Monitoring: Implications for an artificial β-cell,” Diabetes Care, vol. 31, pp. 295–300, February 2008.[DOI]
Sensitivity Measures for Oscillating Systems: Application to Mammalian Circadian Gene Network
S. R. Taylor, R. Gunawan, L. R. Petzold, and F. J. Doyle III, “Sensitivity Measures for Oscillating Systems: Application to Mammalian Circadian Gene Network,” Automatic Control, IEEE Transactions on, vol. 53, pp. 177–188, January 2008.[DOI]
S. R. Taylor, R. Gunawan, L. R. Petzold, and F. J. Doyle III, “Sensitivity Measures for Oscillating Systems: Application to Mammalian Circadian Gene Network,” Automatic Control, IEEE Transactions on, vol. 53, pp. 177–188, January 2008.[DOI]
“Multi-rate model predictive control of particle size distribution in a semibatch emulsion copolymerization reacto
M. T. Dokucu, M.-J. Park, and F. J. Doyle III, “Multi-rate model predictive control of particle size distribution in a semibatch emulsion copolymerization reactor,” Journal of Process Control, vol. 18, pp. 105–120, January 2008.[DOI]
M. T. Dokucu, M.-J. Park, and F. J. Doyle III, “Multi-rate model predictive control of particle size distribution in a semibatch emulsion copolymerization reactor,” Journal of Process Control, vol. 18, pp. 105–120, January 2008.[DOI]
A feasible solution technique for higher-dimensional population balance models
M. A. Pinto, C. D. Immanuel, and F. J. Doyle III, “A feasible solution technique for higher-dimensional population balance models,” Computers & Chemical Engineering, vol. 31, pp. 1242–1256, October 2007.[DOI]
M. A. Pinto, C. D. Immanuel, and F. J. Doyle III, “A feasible solution technique for higher-dimensional population balance models,” Computers & Chemical Engineering, vol. 31, pp. 1242–1256, October 2007.[DOI]
A Molecular Model for Intercellular Synchronization in the Mammalian Circadian Clock
T.-L. To, M. A. Henson, E. D. Herzog, and F. J. Doyle III, “A Molecular Model for Intercellular Synchronization in the Mammalian Circadian Clock,” Biophys J., vol. 92, pp. 3792?3803–3792?3803, June 2007.[DOI].
T.-L. To, M. A. Henson, E. D. Herzog, and F. J. Doyle III, “A Molecular Model for Intercellular Synchronization in the Mammalian Circadian Clock,” Biophys J., vol. 92, pp. 3792?3803–3792?3803, June 2007.[DOI].
Simultaneous high gain and wide dynamic range in a model of bacterial chemotaxis
M. J. Park, F. W. Dahlquist, and F. J. Doyle III, “Simultaneous high gain and wide dynamic range in a model of bacterial chemotaxis,” Systems Biology, IET, vol. 1, pp. 222–229, 2007.[DOI]
M. J. Park, F. W. Dahlquist, and F. J. Doyle III, “Simultaneous high gain and wide dynamic range in a model of bacterial chemotaxis,” Systems Biology, IET, vol. 1, pp. 222–229, 2007.[DOI]
A run-to-run framework for prandial insulin dosing: handling real-life uncertainty
C. C. Palerm, H. Zisser, L. Jovanovic, and F. J. Doyle III, “A run-to-run framework for prandial insulin dosing: handling real-life uncertainty,” International Journal of Robust and Nonlinear Control, vol. 17, pp. 1194–1213, 2007.[DOI]
C. C. Palerm, H. Zisser, L. Jovanovic, and F. J. Doyle III, “A run-to-run framework for prandial insulin dosing: handling real-life uncertainty,” International Journal of Robust and Nonlinear Control, vol. 17, pp. 1194–1213, 2007.[DOI]
Uncovering Physiologic Mechanisms of Circadian Rhythms and Sleep/Wake Regulation through Mathematical Modeling
R. E. Kronauer, G. Gunzelmann, H. P. A. Van Dongen, F. J. Doyle III, and E. B. Klerman, “Uncovering Physiologic Mechanisms of Circadian Rhythms and Sleep/Wake Regulation through Mathematical Modeling,” J Biol Rhythms, vol. 22, pp. 233–245, June 2007.[DOI]
R. E. Kronauer, G. Gunzelmann, H. P. A. Van Dongen, F. J. Doyle III, and E. B. Klerman, “Uncovering Physiologic Mechanisms of Circadian Rhythms and Sleep/Wake Regulation through Mathematical Modeling,” J Biol Rhythms, vol. 22, pp. 233–245, June 2007.[DOI]
“Prandial Insulin Dosing Using Run-to-Run Control: Application of clinical data and medical expertise to define a suitable performance metric
C. C. Palerm, H. Zisser, W. C. Bevier, L. Jovanovic, and F. J. Doyle III, “Prandial Insulin Dosing Using Run-to-Run Control: Application of clinical data and medical expertise to define a suitable performance metric,” Diabetes Care, vol. 30, pp. 1131–1136, May 2007.[DOI]
C. C. Palerm, H. Zisser, W. C. Bevier, L. Jovanovic, and F. J. Doyle III, “Prandial Insulin Dosing Using Run-to-Run Control: Application of clinical data and medical expertise to define a suitable performance metric,” Diabetes Care, vol. 30, pp. 1131–1136, May 2007.[DOI]
Intercellular Coupling Confers Robustness against Mutations in the SCN Circadian Clock Network
A. C. Liu, D. K. Welsh, C. H. Ko, H. G. Tran, E. E. Zhang, A. A. Priest, E. D. Buhr, O. Singer, K. Meeker, I. M. Verma, F. J. Doyle III, J. S. Takahashi, and S. A. Kay, “Intercellular Coupling Confers Robustness against Mutations in the SCN Circadian Clock Network,” Cell, vol. 129, pp. […]
A. C. Liu, D. K. Welsh, C. H. Ko, H. G. Tran, E. E. Zhang, A. A. Priest, E. D. Buhr, O. Singer, K. Meeker, I. M. Verma, F. J. Doyle III, J. S. Takahashi, and S. A. Kay, “Intercellular Coupling Confers Robustness against Mutations in the SCN Circadian Clock Network,” Cell, vol. 129, pp. […]
Phase Sensitivity Analysis of Circadian Rhythm Entrainment
R. Gunawan and F. J. Doyle III, “Phase Sensitivity Analysis of Circadian Rhythm Entrainment,” J Biol Rhythms, vol. 22, pp. 180–194, April 2007.[DOI]
R. Gunawan and F. J. Doyle III, “Phase Sensitivity Analysis of Circadian Rhythm Entrainment,” J Biol Rhythms, vol. 22, pp. 180–194, April 2007.[DOI]
Calculating the insulin to carbohydrate ratio using the hyperinsulinaemic-euglycaemic clamp?-?a novel use for a proven technique
W. C. Bevier, H. Zisser, C. C. Palerm, D. A. Finan, D. E. Seborg, F. J. Doyle III, A. O. Wollitzer, Jovanovi, ccaron, and Lois, “Calculating the insulin to carbohydrate ratio using the hyperinsulinaemic-euglycaemic clamp?-?a novel use for a proven technique,” Diabetes/Metabolism Research and Reviews, vol. 23, pp. 472–478, 2007.[DOI]
W. C. Bevier, H. Zisser, C. C. Palerm, D. A. Finan, D. E. Seborg, F. J. Doyle III, A. O. Wollitzer, Jovanovi, ccaron, and Lois, “Calculating the insulin to carbohydrate ratio using the hyperinsulinaemic-euglycaemic clamp?-?a novel use for a proven technique,” Diabetes/Metabolism Research and Reviews, vol. 23, pp. 472–478, 2007.[DOI]
Quantitative performance metrics for robustness in circadian rhythms
N. Bagheri, J. Stelling, and F. J. Doyle III, “Quantitative performance metrics for robustness in circadian rhythms,” Bioinformatics, vol. 23, pp. 358–364, February 2007.[DOI]
N. Bagheri, J. Stelling, and F. J. Doyle III, “Quantitative performance metrics for robustness in circadian rhythms,” Bioinformatics, vol. 23, pp. 358–364, February 2007.[DOI]
Circadian phase entrainment via nonlinear model predictive control
N. Bagheri, J. Stelling, and F. J. Doyle III, “Circadian phase entrainment via nonlinear model predictive control,” International Journal of Robust and Nonlinear Control, vol. 17, pp. 1555–1571, 2007.[DOI]
N. Bagheri, J. Stelling, and F. J. Doyle III, “Circadian phase entrainment via nonlinear model predictive control,” International Journal of Robust and Nonlinear Control, vol. 17, pp. 1555–1571, 2007.[DOI]
Nonlinear inferential multi-rate control of Kappa number at multiple locations in a continuous pulp digester
N. Padhiyar, A. Gupta, A. Gautam, S. Bhartiya, F. J. Doyle III, S. Dash, and S. Gaikwad, “Nonlinear inferential multi-rate control of Kappa number at multiple locations in a continuous pulp digester,” Journal of Process Control, vol. 16, pp. 1037–1053, December 2006.[DOI]
N. Padhiyar, A. Gupta, A. Gautam, S. Bhartiya, F. J. Doyle III, S. Dash, and S. Gaikwad, “Nonlinear inferential multi-rate control of Kappa number at multiple locations in a continuous pulp digester,” Journal of Process Control, vol. 16, pp. 1037–1053, December 2006.[DOI]
