Developing control systems for medical applications poses significant challenges, some of which are unique to this field. Physiological systems involve a multitude of interacting subsystems and networks, with multiple feedforward and feedback loops. The dynamics vary both between different individuals, and within the same individual over time. Measurement and estimation of both inter- and intra-patient […]
Based at Harvard University, the Doyle group is comprised of a diverse group of researchers, coming from backgrounds such as computer science, biology, and chemical engineering. Contact us to inquire about open positions.
A DNA methylation clock associated with age-related illnesses and mortality is accelerated in men with combat PTSD
Ruoting Yang, Gwyneth W. Y. Wu, Josine E. Verhoeven, Aarti Gautam, Victor I. Reus, Jee In Kang, Janine D. Flory, Duna Abu-Amara, PTSD Systems Biology Consortium, Leroy Hood, Francis J. Doyle III, Rachel Yehuda, Charles R. Marmar, Marti Jett, Rasha Hammamieh, Synthia H. Mellon, & Own M. Wolkowitz. Molecular Pyschiatry, 2020.
Randomized Crossover Comparison of Automated Insulin Delivery vs. Conventional Therapy using an Unlocked Smartphone with Scheduled Pasta and Rice Meal Challenges in the Outpatient Setting
Sunil Deshpande, Jordan E. Pinsker, Mei Mei Church, Molly Piper, Camille Andre, Jennifer Massa, Francis J. Doyle, Dacid M. Eisenberg, and Eyal Dassau. 2020. Diabetes, Technology, and Therapuetics.
Doyle III, Francis J. , Dassau, Eyal, Seborg, Dale E., Lee, Joon Bok. United States Patent Application. 2020.