Developing control systems for medical applications poses significant challenges, some of which are unique to this field. Physiological systems involve a multitude of interacting subsystems and networks, with multiple feedforward and feedback loops. The dynamics vary both between different individuals, and within the same individual over time. Measurement and estimation of both inter- and intra-patient […]
Based at Harvard University, the Doyle group is comprised of a diverse group of researchers, coming from backgrounds such as computer science, biology, and chemical engineering. Contact us to inquire about open positions.
A new animal model of insulin-glucose dynamics in the intraperitoneal space enhances closed-loop control performance
A. Chakrabarty, J. M. Gregory, L. M. Moore, P. E. Williams, B. Farmer, A. D. Cherrington, P. Lord, B. Shelton, D. Cohen, H. C. Zisser, F. J. Doyle III, & E. Dassau. Journal of Process Control. 2019.
A Multivariate Bayesian Optimization Framework for Long-Term Controller Adaptation in Artificial Pancreas
D Shi, E Dassau, FJ Doyle – 2018 IEEE Conference on Decision and Control (CDC), 2018.
Design and Clinical Evaluation of the Interoperable Artificial Pancreas System (iAPS): Interoperable Components with Modular Design for Progressive Artificial Pancreas Research and Developement
S. Deshpande, J. E. Pinsker, S. Zavitsanou, D. Shi, R. Tompot, M. M. Church, C. Andre, F. J. Doyle III, E. Dassau. Diabetes Technology & Therapeutics. 2018.